“危险晶体”
"Dangerous crystals".
作者信息
DeFranco Anthony L
机构信息
Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.
出版信息
Immunity. 2008 Nov 14;29(5):670-1. doi: 10.1016/j.immuni.2008.10.005.
PMID:19006690
Abstract
Uric acid (UA) crystals are a potent stimulator of inflammation, but how they activate immune cells is not known. In this issue of Immunity, Ng et al. (2008) provide evidence suggesting that UA activates the Syk kinase via membrane cholesterol.
摘要
尿酸（UA）晶体是炎症的强效刺激物，但它们如何激活免疫细胞尚不清楚。在本期《免疫》杂志中，Ng等人（2008年）提供的证据表明，尿酸通过膜胆固醇激活Syk激酶。
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