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在儿科急诊科就诊的皮肤脓肿中社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)的患病率。

The prevalence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in skin abscesses presenting to the pediatric emergency department.

作者信息

Magilner David, Byerly Marielle Moses, Cline David M

机构信息

Wake Forest University-School of Medicine, USA.

出版信息

N C Med J. 2008 Sep-Oct;69(5):351-4.

Abstract

BACKGROUND

Community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) infections have been increasing. The most common of these infections present as skin abscesses. The objectives of this study were to prospectively determine the prevalence of CA-MRSA in abscesses in the population of a pediatric emergency department, to determine antibiotic sensitivity patterns of the CA-MRSA isolates, and to describe the patient population that presented with skin abscesses.

METHODS

We conducted a prospective study of children under the age of 18 years who presented to our pediatric emergency department with a skin abscess that required incision and drainage. Pus from these abscesses was sent for culture to determine the causative agent, and antibiotic sensitivities were reported. Characteristics of the patient population that presented with these abscesses were examined.

RESULTS

Sixty-eight patients were enrolled over an 18-month period. Of these, 60 (88%) had cultures positive for Staphylococcus aureus (S. Aureus). Of these 60 patients, 51 (85%) were identified as CA-MRSA by their resistance patterns. All of the CA-MRSA isolates were sensitive to trimethoprim/sulfamethoxisole; 6 (10%) were either resistant or intermittently resistant to clindamycin.

LIMITATIONS

The study was conducted on a convenience sample of patients and enrolled a relatively small number of patients.

CONCLUSIONS

CA-MRSA is responsible for the vast majority of skin abscesses presenting to the pediatric emergency department. CA-MRSA isolates are likely to be sensitive to trimethoprim/sulfamethoxisole or clindamycin, although there is some resistance to clindamycin.

摘要

背景

社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)感染一直在增加。这些感染最常见的表现为皮肤脓肿。本研究的目的是前瞻性地确定儿科急诊科人群中脓肿患者的CA-MRSA患病率,确定CA-MRSA分离株的抗生素敏感性模式,并描述出现皮肤脓肿的患者群体。

方法

我们对18岁以下因皮肤脓肿到儿科急诊科就诊且需要切开引流的儿童进行了一项前瞻性研究。将这些脓肿的脓液送去培养以确定病原体,并报告抗生素敏感性。检查了出现这些脓肿的患者群体的特征。

结果

在18个月期间共纳入68例患者。其中,60例(88%)金黄色葡萄球菌培养阳性。在这60例患者中,51例(85%)根据耐药模式被鉴定为CA-MRSA。所有CA-MRSA分离株对甲氧苄啶/磺胺甲恶唑敏感;6例(10%)对克林霉素耐药或间歇性耐药。

局限性

本研究是对方便样本患者进行的,纳入的患者数量相对较少。

结论

CA-MRSA是儿科急诊科出现的绝大多数皮肤脓肿的病因。CA-MRSA分离株可能对甲氧苄啶/磺胺甲恶唑或克林霉素敏感,尽管对克林霉素存在一些耐药性。

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