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绝经后女性的雌激素和孕激素治疗

Estrogen and progestogen therapy in postmenopausal women.

出版信息

Fertil Steril. 2008 Nov;90(5 Suppl):S88-102. doi: 10.1016/j.fertnstert.2008.08.091.

DOI:10.1016/j.fertnstert.2008.08.091
PMID:19007655
Abstract

This Educational Bulletin discusses the effectiveness of hormone therapy (HT) for relieving vasomotor and urogenital symptoms and the side effects associated with such treatment; considers the evidence concerning the effects of HT on the risk of osteoporosis and related fractures and on the risks of coronary artery disease, dementia, and colorectal cancer; and considers the longer term effects of HT on the risks of stroke, venous thromboembolism, and cancer of the breast, endometrium, and ovary.

摘要

本教育公告讨论了激素疗法(HT)缓解血管舒缩症状和泌尿生殖系统症状的有效性以及该治疗相关的副作用;考量了有关HT对骨质疏松症及相关骨折风险、冠状动脉疾病、痴呆症和结直肠癌风险影响的证据;并考量了HT对中风、静脉血栓栓塞以及乳腺癌、子宫内膜癌和卵巢癌风险的长期影响。

相似文献

1
Estrogen and progestogen therapy in postmenopausal women.绝经后女性的雌激素和孕激素治疗
Fertil Steril. 2008 Nov;90(5 Suppl):S88-102. doi: 10.1016/j.fertnstert.2008.08.091.
2
Estrogen and progestogen therapy in postmenopausal women.绝经后女性的雌激素和孕激素治疗
Fertil Steril. 2006 Nov;86(5 Suppl 1):S75-88. doi: 10.1016/j.fertnstert.2006.07.1476.
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Landmark hormone replacement therapy study stopped after finding more harms than benefits.具有里程碑意义的激素替代疗法研究在发现弊大于利后停止。
Rep Med Guidel Outcomes Res. 2002 Aug 9;13(15):5-7.
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Estrogen and progestogen therapy in postmenopausal women.绝经后女性的雌激素和孕激素疗法
Fertil Steril. 2004 Sep;82 Suppl 1:S70-80. doi: 10.1016/j.fertnstert.2004.05.006.
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Hormone replacement therapy: estrogen after menopause.激素替代疗法:绝经后的雌激素。
Pharmacotherapy. 1996 May-Jun;16(3):366-75.
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Hormone replacement therapy in postmenopausal women.绝经后女性的激素替代疗法。
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Postmenopausal hormone therapy and breast cancer.绝经后激素治疗与乳腺癌
Prescrire Int. 2009 Apr;18(100):66-7.
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Postmenopausal hormone replacement therapy: does the progestin make a difference?绝经后激素替代疗法:孕激素有影响吗?
J S C Med Assoc. 2002 Feb;98(1):12-9.
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Progestogens and venous thromboembolism among postmenopausal women using hormone therapy.绝经后激素治疗女性的孕激素与静脉血栓栓塞症。
Maturitas. 2011 Dec;70(4):354-60. doi: 10.1016/j.maturitas.2011.10.002. Epub 2011 Oct 22.
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Risks and benefits of long-term treatment with estrogens.雌激素长期治疗的风险与益处。
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引用本文的文献

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The Role of Estrogen Therapy as a Protective Factor for Alzheimer's Disease and Dementia in Postmenopausal Women: A Comprehensive Review of the Literature.雌激素疗法作为绝经后女性阿尔茨海默病和痴呆症保护因素的作用:文献综述
Cureus. 2023 Aug 6;15(8):e43053. doi: 10.7759/cureus.43053. eCollection 2023 Aug.
2
Sex hormone drives blood stem cell reproduction.性激素驱动血液干细胞再生。
EMBO J. 2014 Mar 18;33(6):534-5. doi: 10.1002/embj.201487976. Epub 2014 Feb 20.
3
Estrogen plus progestin and colorectal cancer incidence and mortality.
雌激素加孕激素与结直肠癌发病率和死亡率。
J Clin Oncol. 2012 Nov 10;30(32):3983-90. doi: 10.1200/JCO.2012.42.7732. Epub 2012 Sep 24.
4
Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis.在支持突触重塑和神经发生的海马亚区中,孕激素受体膜成分-1(Pgrmc1)和经典孕激素受体(Pgr)对 17β-雌二醇和孕激素的反应不同。
Endocrinology. 2012 Feb;153(2):759-69. doi: 10.1210/en.2011-1699. Epub 2011 Dec 6.
5
Guidelines and recommendations on hormone therapy in the menopause.更年期激素治疗指南与建议
J Midlife Health. 2010 Jan;1(1):41-2. doi: 10.4103/0976-7800.66990.
6
The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.内源性选择性雌激素受体调节剂 27-羟胆固醇是骨内稳态的负调节剂。
Endocrinology. 2010 Aug;151(8):3675-85. doi: 10.1210/en.2010-0080. Epub 2010 May 25.
7
Cognitive benefits of hormone therapy: cardiovascular factors and healthy-user bias.激素治疗的认知益处:心血管因素和健康使用者偏差。
Maturitas. 2009 Nov 20;64(3):182-7. doi: 10.1016/j.maturitas.2009.09.014. Epub 2009 Oct 29.
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Combined hormone therapy at menopause and breast cancer: a warning--short-term use increases risk.更年期联合激素治疗与乳腺癌:一则警示——短期使用会增加风险。
J Clin Oncol. 2009 Nov 1;27(31):5116-9. doi: 10.1200/JCO.2009.23.9988. Epub 2009 Sep 14.