在接受手动融合的123I-MIBG单光子发射计算机断层扫描（SPECT）和计算机断层扫描（CT）图像的131I-MIBG治疗的恶性嗜铬细胞瘤患者中转移灶的定位

Localization of metastases from malignant pheochromocytoma in patients undergoing 131I-MIBG therapy with manually fused 123I-MIBG SPECT and CT images.

作者信息

Kizu Hiroto, Takayama Teruhiko, Tsushima Hiroyuki, Noguchi Atsushi, Nakajima Kenichi, Onoguchi Masahisa, Kinuya Seigo

机构信息

Department of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.

出版信息

J Nucl Med Technol. 2008 Dec;36(4):186-8. doi: 10.2967/jnmt.108.051656. Epub 2008 Nov 13.

DOI:10.2967/jnmt.108.051656

PMID:19008288

Abstract

(131)I-metaiodobenzylguanidine (MIBG) has been used as a therapeutic agent for pheochromocytoma. Tumor localization and precise staging are essential for therapy with high-dose (131)I-MIBG. The sites and extent of (123)I-MIBG uptake are usually estimated to predict the effectiveness of therapy before administration. However, conventional scintigraphic images provide insufficient anatomic information. Therefore, we tried to manually superimpose (123)I-MIBG SPECT and CT images using free software.

摘要

（131）碘间位碘代苄胍（MIBG）已被用作嗜铬细胞瘤的治疗药物。肿瘤定位和精确分期对于高剂量（131）I-MIBG治疗至关重要。在给予（123）I-MIBG之前，通常通过估计其摄取部位和范围来预测治疗效果。然而，传统的闪烁扫描图像提供的解剖信息不足。因此，我们尝试使用免费软件手动叠加（123）I-MIBG单光子发射计算机断层扫描（SPECT）和计算机断层扫描（CT）图像。