欧洲各地区健康非亲属异性伴侣中高血压的患病率、知晓率、治疗率及控制率：不同心肌梗死风险的欧洲社区饮食习惯概况——以移民为基因-环境相互作用模型项目的影响

Prevalence, awareness, treatment and control of hypertension in healthy unrelated male-female pairs of European regions: the dietary habit profile in European communities with different risk of myocardial infarction--the impact of migration as a model of gene-environment interaction project.

作者信息

Costanzo Simona, Di Castelnuovo Augusto, Zito Francesco, Krogh Vittorio, Siani Alfonso, Arnout Jozef, Cappuccio Francesco P, Miller Michelle A, van Dongen Martien, de Lorgeril Michel, de Gaetano Giovanni, Donati Maria Benedetta, Iacoviello Licia

机构信息

Laboratory of Genetic and Environmental Epidemiology, Research Laboratories, John Paul II Center for High Technology Research, Care and Education in Biomedical Sciences, Catholic University, Campobasso, Italy.

出版信息

J Hypertens. 2008 Dec;26(12):2303-11. doi: 10.1097/HJH.0b013e328311ce04.

DOI:10.1097/HJH.0b013e328311ce04

PMID:19008709

Abstract

BACKGROUND

Blood pressure control is of great importance in the prevention of cardiovascular events.

AIM

To determine the prevalence, awareness, treatment and control of hypertension in healthy unrelated male-female pairs of European regions.

METHODS

The dietary habit profile in European communities with different risk of myocardial infarction: the impact of migration as a model of gene-environment interaction (IMMIDIET) project was a cross-sectional study to investigate differences in the distribution of cardiovascular risk factors and dietary habits in healthy unrelated male-female pairs married or living together in European regions. Eight hundred and two unrelated male-female pairs were randomly recruited in Abruzzo (Italy), Limburg (Belgium) and south-west London (England). Blood pressure was measured using an automated device. Hypertension was defined as systolic blood pressure of at least 140 mmHg or diastolic blood pressure of at least 90 mmHg or current antihypertensive treatment.

RESULTS

Overall, 24.4% of the population was hypertensive; among them, one-third was on antihypertensive treatment, but a significant proportion (56%) was unaware of the high blood pressure levels. Men were more often hypertensive than women (29.4 vs. 19.5%, P < 0.0001). Women were more often treated than men (49.8 vs. 28.9%, P < 0.0001). Women from south-west London showed blood pressure levels lower than those from Abruzzo and Limburg (P < 0.001 for both, adjusted for age, BMI and social status). No difference among countries was found in blood pressure levels in men. The adjusted prevalence of hypertension was 20.8% in south-west London, 23.6% in Limburg and 28.87% in Abruzzo (Abruzzo vs. south-west London P = 0.005). The prevalence of antihypertensive treatment was 43.5, 42.5 and 32.1% in Abruzzo, Limburg and south-west London, respectively. Out of those treated for hypertension, 42, 43 and 47.7% in Abruzzo, Limburg and south-west London, respectively, were well controlled.

CONCLUSION

In communities of healthy unrelated male-female pairs from three different European regions, more than half of hypertensive patients appeared to have blood pressure levels not at target values. Interventions are required to optimize the use and effectiveness of antihypertensive drug therapy in these patients.

摘要

背景

血压控制对预防心血管事件至关重要。

目的

确定欧洲地区健康非亲属异性伴侣中高血压的患病率、知晓率、治疗率和控制率。

方法

欧洲不同心肌梗死风险社区的饮食习惯概况：以移民作为基因 - 环境相互作用模型的影响（IMMIDIET）项目是一项横断面研究，旨在调查在欧洲地区已婚或同居的健康非亲属异性伴侣中心血管危险因素分布和饮食习惯的差异。在意大利阿布鲁佐、比利时林堡和英国伦敦西南部随机招募了802对非亲属异性伴侣。使用自动设备测量血压。高血压定义为收缩压至少140 mmHg或舒张压至少90 mmHg或正在接受抗高血压治疗。

结果

总体而言，24.4%的人群患有高血压；其中，三分之一正在接受抗高血压治疗，但很大一部分（56%）未意识到自己血压高。男性患高血压的比例高于女性（29.4%对19.5%，P < 0.0001）。女性接受治疗的比例高于男性（49.8%对28.9%，P < 0.0001）。伦敦西南部的女性血压水平低于阿布鲁佐和林堡的女性（年龄、体重指数和社会地位调整后，两者P均< 0.001）。各国男性的血压水平未发现差异。调整后的高血压患病率在伦敦西南部为20.8%，在林堡为23.6%，在阿布鲁佐为28.87%（阿布鲁佐与伦敦西南部相比，P = 0.005）。阿布鲁佐、林堡和伦敦西南部接受抗高血压治疗的比例分别为43.5%（阿布鲁佐）、42.5%（林堡）和32.1%（伦敦西南部）。在接受高血压治疗的患者中，阿布鲁佐、林堡和伦敦西南部分别有42%、43%和47.7%的患者血压得到良好控制。