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鸭雏和鹅雏经莱德尼采(雅巴1)病毒实验感染后的病毒血症和抗体形成研究。

Studies on viremia and antibody formation in ducklings and goslings after experimental infection with Lednice (Yaba 1) virus.

作者信息

Danielová V, Málková D

出版信息

Folia Parasitol (Praha). 1976;23(4):367-72.

PMID:190088
Abstract

A very low virus level was found for a short time in the blood of ducklings and goslings after experimental Lednice (Yaba 1) virus infection by subcutaneous (scut) and intranasal (inas) route and in blood of ducklings also after infection by intracerebral (icer) route. Subsequently virus neutralizing antibody formation was examined. Antibody formation was found in most of animals. In goslings onset of antibody formation seems to be slower than in ducklings after the same virus infection dose; vice versa, in ducklings antibody titer decreased after 6 weeks. Using low infection virus dose, neutralizing antibody level in ducklings was lower than in the former case. On examining the blood and the organs, the virus was detected in a very low amount and for a very short time in blood and spleen of goslings and only in blood of ducklings.

摘要

通过皮下(scut)和鼻内(inas)途径对雏鸭和雏鹅进行实验性莱德尼采(雅巴1)病毒感染后,在雏鸭和雏鹅血液中短时间内发现病毒水平非常低,通过脑内(icer)途径感染雏鸭后,其血液中也出现这种情况。随后检测了病毒中和抗体的形成。在大多数动物中发现了抗体形成。在相同病毒感染剂量下,雏鹅抗体形成的开始似乎比雏鸭慢;反之,雏鸭的抗体滴度在6周后下降。使用低感染病毒剂量时,雏鸭的中和抗体水平低于前一种情况。在检查血液和器官时,在雏鹅的血液和脾脏中以及仅在雏鸭的血液中检测到极少量且极短时间的病毒。

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