Tuter N V
Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(11):55-7.
Panic disorder (PD) is a state characterized by a complex of psychiatric and autonomic symptoms. The high frequency of autonomic symptoms in PD suggests the necessity of evaluation of the autonomic nervous system state. For this purpose, author used the method of evoked skin sympathetic potentials (ESSP). ESSP per se is a result of the reflex which includes three patterns: afferent, central and efferent. Patients with DSM-IV diagnosis of PD were stratified into three nosological groups: neurotic, personality disorders and schizotypal pathology. A study of ESSP revealed the significant increase of latency in all groups regardless of their mental status as compared to the controls. A role of central mechanisms (the increase of time of the central delay) appears to be the most plausible in the genesis of the ESSP latency increase in PD.
惊恐障碍（PD）是一种以一系列精神和自主神经症状为特征的状态。PD中自主神经症状的高发生率表明有必要评估自主神经系统状态。为此，作者采用了诱发皮肤交感神经电位（ESSP）的方法。ESSP本身是一种反射的结果，该反射包括三种模式：传入、中枢和传出。根据《精神疾病诊断与统计手册》第四版（DSM-IV）诊断为PD的患者被分为三个疾病学组：神经症、人格障碍和分裂样病理。对ESSP的研究表明，与对照组相比，所有组的潜伏期均显著增加，无论其精神状态如何。在PD中ESSP潜伏期增加的发生过程中，中枢机制（中枢延迟时间增加）的作用似乎最为合理。
