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通过胸腺嘧啶酸修饰的两亲性分子在序列选择性DNA模板自组装过程中形成纳米纤维。

Nanofiber formation from sequence-selective DNA-templated self-assembly of a thymidylic acid-appended bolaamphiphile.

作者信息

Iwaura Rika, Ohnishi-Kameyama Mayumi, Shimizu Toshimi

机构信息

National Food Research Institute, National Agriculture and Food Research Organization, 2-1-12, Kannondai, Tsukuba, 305-8642, Ibaraki, Japan.

出版信息

Chem Commun (Camb). 2008 Nov 30(44):5770-2. doi: 10.1039/b813592d. Epub 2008 Oct 8.

Abstract

Quaternary self-assembly of a thymidylic acid-appended bolaamphiphile, with heteropolymeric DNA as a template, produced supramolecular helical nanofibers in the presence of specific target DNA.

摘要

以杂聚DNA为模板,胸腺嘧啶酸连接的双亲性分子进行四级自组装,在特定靶标DNA存在的情况下产生超分子螺旋纳米纤维。

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