肠道中的 Cajal 间质细胞——胃肠病学家的观点
Interstitial cells of Cajal in the gut--a gastroenterologist's point of view.
作者信息
Negreanu Lucian M, Assor Philippe, Mateescu Bogdan, Cirstoiu Catalin
机构信息
Department of Hepato-Gastroenterology, Trousseau University Hospital Center, Tours, France.
出版信息
World J Gastroenterol. 2008 Nov 7;14(41):6285-8. doi: 10.3748/wjg.14.6285.
Abstract
Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specific treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, infantile hypertrophic pyloric stenosis, chronic intestinal pseudo-obstruction and slow transit constipation. Moreover we discuss the role of the Cajal cells in the development of stromal tumors of the gastrointestinal tract.
摘要
据报道，在许多肠道疾病中都存在 Cajal 间质细胞（ICC）正常功能的改变。其受累情况的诊断较为罕见，但对于提出特定治疗方案而言是必要的。本文综述了 ICC 在贲门失弛缓症、胃食管反流病、婴儿肥厚性幽门狭窄、慢性假性肠梗阻和慢传输型便秘发病机制中的地位。此外，我们还讨论了 Cajal 细胞在胃肠道间质瘤发生发展中的作用。
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