Hiligsmann M, Bruyère O, Pire G, Reginster J Y
Département d'Economie, HEC-ULg, Université de Liège, Belgique.
Rev Med Liege. 2008 Oct;63(10):588-94.
The Province of Liège has conducted an osteoporosis screening strategy for women aged 50 to 69 years. The objective of this study is to investigate the economic characteristics of the screening strategy and to assess its cost-effectiveness, using a Markov microsimulation model. Our analyses suggest that the osteoporosis screening strategy is efficient if the medical community and the patients fulfill the recommendations of the Province of Liège health authorities and if persistence is optimized. Therefore, bone mineral density (BMD) measurement should be performed in all individuals with positive ultrasound screening; individuals having a positive BMD diagnosis should be treated and adherence to therapy should be increased. Furthermore, to improve the efficiency of the screening strategy, we suggest to target screening on women with one or more clinical risk factors, or on women aged 65 years and older.
列日省针对50至69岁的女性实施了一项骨质疏松症筛查策略。本研究的目的是使用马尔可夫微观模拟模型,调查该筛查策略的经济特征并评估其成本效益。我们的分析表明,如果医疗界和患者遵循列日省卫生当局的建议,并且优化持续性,那么骨质疏松症筛查策略就是有效的。因此,应对所有超声筛查呈阳性的个体进行骨密度(BMD)测量;骨密度诊断呈阳性的个体应接受治疗,并应提高治疗依从性。此外,为了提高筛查策略的效率,我们建议将筛查目标对准有一个或多个临床风险因素的女性,或65岁及以上的女性。