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[我们何时应切除结直肠癌肝转移灶?]

[When should we resect colorectal liver metastases?].

作者信息

Honoré C, Detry O, Deroover A, Piront P, Polus M, Honoré P, Meurisse M

机构信息

Service de Chirurgie Abdominale, Sénologique, Endocrine et de Transplantation, CHU Sart Tilman, Liège, Belgique.

出版信息

Rev Med Liege. 2008 Oct;63(10):595-9.

Abstract

6000 new cases of colorectal cancer are diagnosed each year in Belgium. 50% of these patients shall develop liver metastasis. Resection remains the only chance of long term survival and must be considered as an endpoint from the beginning of the treatment. It is the result of a multidisciplinary discussion and a global approach of the disease. It is rarely directly feasible, but there are many techniques which may make it achievable in the end. Today, resection criteria are exclusively technical and neither bad prognosis factors, nor the presence of extra-hepatic metastases should exclude liver resection. This resection must be assessed by a confirmed hepatobiliary surgeon and must be proposed to all patients whatever their age as long as their general state of health is good.

摘要

比利时每年有6000例新诊断的结直肠癌病例。其中50%的患者会发生肝转移。肝切除仍然是长期生存的唯一机会,从治疗开始就必须将其视为一个终点。这是多学科讨论和对该疾病整体治疗方法的结果。肝切除很少能直接实施,但有许多技术最终可能使其得以实现。如今,肝切除标准完全是技术性的,不良预后因素或肝外转移的存在都不应排除肝切除。这种肝切除必须由经验证的肝胆外科医生进行评估,并且只要患者的总体健康状况良好,无论其年龄多大,都应向所有患者提出肝切除建议。

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