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十多年前接受多菌型麻风治疗的患者的神经性疼痛。

Neuropathic pain in people treated for multibacillary leprosy more than ten years previously.

作者信息

Saunderson Paul, Bizuneh Elizabeth, Leekassa Ruth

机构信息

American Leprosy Missions, Greenville, SC 29601, USA.

出版信息

Lepr Rev. 2008 Sep;79(3):270-6.

Abstract

OBJECTIVES

To identify patients with typical symptoms of neuropathic pain in a well-defined cohort of multibacillary patients being followed up as part of a relapse study in Ethiopia; to identify risk factors for the development of neuropathic pain.

DESIGN

96 patients who had completed MDT more than 10 years previously participated in the study, through a questionnaire.

RESULTS

28 (29%) had symptoms of neuropathic pain and it was reported as severe in 12. Because the past history of these subjects is well documented, a risk factor analysis was carried out. The presence of leprosy-related impairment was the only significant risk factor for neuropathic pain that was identified.

CONCLUSIONS

Neuropathic pain is an important problem in a proportion of people previously treated for leprosy. Further research into the management of the condition is required.

摘要

目的

在埃塞俄比亚一项作为复发研究一部分而进行随访的明确界定的多菌型患者队列中,识别有神经性疼痛典型症状的患者;识别神经性疼痛发生的危险因素。

设计

96名10多年前已完成多药联合化疗的患者通过问卷调查参与了该研究。

结果

28名(29%)有神经性疼痛症状,其中12名报告症状严重。由于这些受试者的既往病史记录完善,因此进行了危险因素分析。发现与麻风病相关的损伤是唯一确定的神经性疼痛重要危险因素。

结论

神经性疼痛在一部分既往接受过麻风病治疗的人群中是一个重要问题。需要对该病的管理进行进一步研究。

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