Cools Toon, De Veylder Lieven
Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), Ghent, Belgium.
Curr Opin Plant Biol. 2009 Feb;12(1):23-8. doi: 10.1016/j.pbi.2008.09.012. Epub 2008 Nov 14.
Plants are sedentary, and so have unavoidably close contact with agents that target their genome integrity. To sense and react to these threats, plants have evolved DNA stress checkpoint mechanisms that arrest the cell cycle and activate the DNA repair machinery to preserve the genome content. Although the pathways that maintain DNA integrity are largely conserved among eukaryotic organisms, plants put different accents on cell cycle control under DNA stress and might have their own way to cope with it.
植物是固着生长的，因此不可避免地会与针对其基因组完整性的因子密切接触。为了感知并应对这些威胁，植物进化出了DNA应激检查点机制，该机制会使细胞周期停滞，并激活DNA修复机制以维持基因组的完整性。尽管维持DNA完整性的途径在真核生物中在很大程度上是保守的，但植物在DNA应激下对细胞周期控制有着不同的侧重点，并且可能有自己应对DNA应激的方式。
