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[一名63岁患者因伪结核棒状杆菌引起的腋窝淋巴结炎]

[Axillary lymphadenitis due to Corynebacterium pseudotuberculosis in a 63-year-old patient].

作者信息

Hémond V, Rosenstingl S, Auriault M L, Galanti M J, Gatfosse M

机构信息

Service de médecine interne A, hôpital René-Albertier, rue Gabriel-Péri, 77527 Coulommiers cedex, France.

出版信息

Med Mal Infect. 2009 Feb;39(2):136-9. doi: 10.1016/j.medmal.2008.09.029. Epub 2008 Nov 13.

DOI:10.1016/j.medmal.2008.09.029
PMID:19013041
Abstract

A 63-year-old woman living in a rural area presented in 2004 with a granulomatous necrotizing axillary lymphadenitis caused by Corynebacterium pseudotuberculosis, a Gram positive bacillus belonging to the group of Corynebacterium diphtheriae, which is found primarily in animal infections. In the human being, around 30 cases of infection due to C. pseudotuberculosis have been described, mainly among people working in contact with infected animals. For this reason, this infection, which induces exclusively lymphadenitis and abscesses with granulomatous necrotizing lesions, should be regarded as an occupational disease. In this patient, due to ignorance of the disease, this bacterium was considered to be merely saprophytic. The first treatment introduced was probabilistic antibiotherapy followed by a second course of antibiotics after aspiration. The trend confirmed that this was not the correct treatment and that surgery was the only way to achieve a cure.

摘要

一名63岁的农村妇女于2004年就诊,患有由伪结核棒状杆菌引起的肉芽肿性坏死性腋窝淋巴结炎。伪结核棒状杆菌是一种革兰氏阳性杆菌,属于白喉棒状杆菌属,主要见于动物感染。在人类中,已报道约30例由伪结核棒状杆菌引起的感染病例,主要发生在与感染动物有接触的人群中。因此,这种仅引起淋巴结炎和伴有肉芽肿性坏死病变的脓肿的感染应被视为一种职业病。在该患者中,由于对该疾病的无知,这种细菌最初被认为只是腐生菌。最初采用的治疗方法是经验性抗菌治疗,抽吸后又进行了第二个疗程的抗生素治疗。病情发展证实这不是正确的治疗方法,手术是实现治愈的唯一途径。

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