Novak Thomas E, Salmasi Amirali Hassanzadeh, Lakshmanan Yegappan, Mathews Ranjiv I, Gearhart John P
Division of Pediatric Urology, James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
J Urol. 2009 Jan;181(1):310-4; discussion 314. doi: 10.1016/j.juro.2008.09.036. Epub 2008 Nov 14.
We report the indications, technique and outcome of a large series of children who underwent bladder neck transection for intractable urinary incontinence.
We retrospectively reviewed demographics, operative details, complications and outcomes of 76 patients (47 males, 29 females) who underwent bladder neck closure at our institution between 1996 and 2006. Mean patient age at the time of the procedure was 12 years, 10 months. The most common diagnosis was bladder exstrophy. Of the patients 31 had undergone prior bladder neck reconstruction (30) or sling repair (1). All patients underwent concomitant augmentation and creation of a catheterizable stoma.
A total of 50 patients had more than 12 months of followup (mean 44, range 12 to 128). Continence was achieved initially in 86% of the patients (43 of 50). Of the 7 primary failures 2 leaked via the urethra and 5 via the stoma. Six of these patients achieved dryness with revision, for a final continence rate of 98%. A single renal unit suffered significant loss of function during this period. New, nonobstructive hydronephrosis developed in 8 additional renal units. Stones developed in 30% of the patients. There were no spontaneous bladder ruptures.
Bladder neck transection in combination with enterocystoplasty and creation of a continent catheterizable stoma is an effective approach to incontinent cases with severely damaged bladder outlets and poor quality bladders in which other reconstructive approaches either have failed or are deemed likely to fail. Specific concerns regarding the risk of poor renal outcomes and perforation seem unwarranted at present.
我们报告了一系列因顽固性尿失禁接受膀胱颈横断术的儿童的手术指征、技术及结果。
我们回顾性分析了1996年至2006年间在我院接受膀胱颈闭合术的76例患者(47例男性,29例女性)的人口统计学资料、手术细节、并发症及结果。手术时患者的平均年龄为12岁10个月。最常见的诊断是膀胱外翻。其中31例患者曾接受过膀胱颈重建术(30例)或吊带修复术(1例)。所有患者均同时接受了膀胱扩大术并建立了可控性造口。
共有50例患者获得了超过12个月的随访(平均44个月,范围12至128个月)。最初86%的患者(50例中的43例)实现了控尿。7例初次手术失败的患者中,2例经尿道漏尿,5例经造口漏尿。其中6例患者经修复后实现了干爽,最终控尿率为98%。在此期间,有一个肾单位功能严重受损。另有8个肾单位出现了新的、非梗阻性肾积水。30%的患者出现了结石。未发生自发性膀胱破裂。
膀胱颈横断术联合肠膀胱扩大术及建立可控性造口是治疗膀胱出口严重受损且膀胱质量差的尿失禁病例的有效方法,对于其他重建方法已失败或被认为可能失败的此类病例尤为适用。目前,对肾功能不良风险和穿孔风险的特定担忧似乎并无必要。