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中国农村高血压女性中代谢综合征的高患病率。

High prevalence of the metabolic syndrome in hypertensive rural Chinese women.

作者信息

Zhang Xingang, Sun Zhaoqing, Zhang Dayi, Zheng Liqiang, Liu Shuangshuang, Xu Changlu, Li Jiajin, Li Jue, Hu Dayi, Sun Yingxian

机构信息

Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, 110004, PR China.

出版信息

Acta Cardiol. 2008 Oct;63(5):591-8. doi: 10.2143/AC.63.5.2033226.

Abstract

BACKGROUND

The metabolic syndrome has become a major public health issue worldwide.This study was designed to evaluate and compare the epidemiological features of the metabolic syndrome in hypertensive rural Chinese women.

METHODS AND RESULTS

A cross-sectional survey was conducted during 2004-2006, which undertook cluster multistage sampling to a representation sample of hypertensive women living in 50 rural villages of Liaoning, China. A total of 3607 women aged > or =35 years were selected.At baseline, lifestyle and other factors were obtained. The metabolic syndrome was proposed by the International Diabetes Federation definition. Of the study population 49.6% (age-adjusted: 49.3%) had metabolic syndrome. Overall, 64.7%, 39.2%, 33.8%, and 33.9% of the hypertensive women had central obesity, hypertriglyceridaemia, low HDL cholesterol, and high fasting plasma glucose, respectively. 87.7% of the sample had at least one component of the metabolic syndrome. Multivariate logistic regression revealed that Mongolian nationality and obesity were risk factors for metabolic syndrome. Moderate levels of physical activity and current drinking status were shown as protective factors. There was a positive association between metabolic syndrome and age in the age group between 55 and 64 years.

CONCLUSIONS

The current study demonstrated that the prevalence of metabolic syndrome was dramatically high in hypertensive women, even in the rural areas of China. Further, our study indicated that remarkable ethnic differences exist in the prevalence of metabolic syndrome. Obese and moderate levels of physical activity were a modifiable risk factor.

摘要

背景

代谢综合征已成为全球主要的公共卫生问题。本研究旨在评估和比较中国农村高血压女性中代谢综合征的流行病学特征。

方法与结果

2004年至2006年进行了一项横断面调查,对居住在中国辽宁省50个农村的高血压女性代表性样本进行整群多阶段抽样。共选取了3607名年龄≥35岁的女性。在基线时,获取了生活方式和其他因素。代谢综合征采用国际糖尿病联盟的定义。在研究人群中,49.6%(年龄调整后:49.3%)患有代谢综合征。总体而言,高血压女性中分别有64.7%、39.2%、33.8%和33.9%患有中心性肥胖、高甘油三酯血症、低高密度脂蛋白胆固醇和高空腹血糖。87.7%的样本至少有一项代谢综合征组分。多因素逻辑回归显示,蒙古族和肥胖是代谢综合征的危险因素。中等水平的体力活动和当前饮酒状况为保护因素。在55至64岁年龄组中,代谢综合征与年龄呈正相关。

结论

当前研究表明,即使在中国农村地区,高血压女性中代谢综合征的患病率也极高。此外,我们的研究表明代谢综合征患病率存在显著的种族差异。肥胖和中等水平的体力活动是可改变的危险因素。

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