大肠杆菌O157:H7是伊朗设拉子患血性腹泻儿童中的常见病原体吗？

Is Escherichia coli O157:H7 a common pathogen in children with bloody diarrhea in Shiraz, Iran?

作者信息

Alborzi Abdolvahab, Aelami Mohammad Hassan, Astaneh Behrooz, Pourabbas Bahman, Farshad Shohreh, Kalani Mehdi, Nasiri Jalil, Rashidi Mahmood

机构信息

Prof Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Turk J Pediatr. 2008 Jul-Aug;50(4):349-53.

PMID:19014048

Abstract

Escherichia coli (E. coli) O157:H7 is a common cause of bloody diarrhea in developed countries. The aim of this study was to determine whether E. coli O157:H7 is a possible pathogen of bloody diarrhea in southern Iran. Out of 719 children with diarrhea, 243 (34%) patients with positive occult blood took part in our study. The polyclonal antibody test and polymerase chain reaction (PCR) were used to identify E. coli O157:H7. Stool cultures showed enteropathogens in 107 patients (44%). Shigella (34.3%) was followed by E. coli (8.6%), campylobacter (2%) and salmonella (0.4%). None of the E. coli species was of O157:H7 serotype. Antibiotic sensitivity of shigella species was 100% to ceftriaxone, ciprofloxacin and ceftazidime, 94% to nalidixic acid and 13% to co-trimoxazole. The results of the study showed that E. coli O157:H7 is not a cause of bloody diarrhea in our area.

摘要

大肠杆菌O157:H7是发达国家血性腹泻的常见病因。本研究的目的是确定大肠杆菌O157:H7是否为伊朗南部血性腹泻的可能病原体。在719名腹泻儿童中，243名（34%）潜血阳性患者参与了我们的研究。采用多克隆抗体检测和聚合酶链反应（PCR）来鉴定大肠杆菌O157:H7。粪便培养显示107名患者（44%）有肠道病原体。志贺菌（34.3%）之后是大肠杆菌（8.6%）、弯曲杆菌（2%）和沙门氏菌（0.4%）。所有大肠杆菌菌株均非O157:H7血清型。志贺菌属对头孢曲松、环丙沙星和头孢他啶的抗生素敏感性为100%，对萘啶酸的敏感性为94%，对复方新诺明的敏感性为13%。研究结果表明，大肠杆菌O157:H7不是我们地区血性腹泻的病因。