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一名非白血病患者的右肱骨粒细胞肉瘤。

Granulocytic sarcoma of the right humerus in a non-leukaemia patient.

作者信息

Rodríguez Pérez Aurora, López Carrizosa Maria Concepcion, Villalón Blanco Lucia, Samper Ots Pilar Maria, Ortiz Cruz Eduardo

机构信息

Radiation Oncology Department, Hospital Central de la Defensa Gómez-Ulla, Madrid, Spain.

出版信息

Clin Transl Oncol. 2008 Nov;10(11):758-60. doi: 10.1007/s12094-008-0283-9.

DOI:10.1007/s12094-008-0283-9
PMID:19015073
Abstract

Granulocytic sarcoma (GS), an uncommon solid extramedullary tumour, should be considered even in the absence of leukaemia, as delay in diagnosis and treatment worsens the prognosis. We present a GS (single humeral bone lesion) in a non-leukaemia patient, treated with intensive AML (Acute Myeloid Leukaemia) chemotherapy and sequential radiotherapy, in complete response 26 months after diagnosis, confirmed by histopathology and without leukaemia progression.

摘要

粒细胞肉瘤(GS)是一种罕见的髓外实体肿瘤,即使在没有白血病的情况下也应予以考虑,因为诊断和治疗的延迟会使预后恶化。我们报告了一例非白血病患者的GS(单一肱骨骨病变),采用强化急性髓系白血病(AML)化疗及序贯放疗进行治疗,诊断后26个月完全缓解,经组织病理学证实且无白血病进展。

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本文引用的文献

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Granulocytic sarcoma: 32 cases and review of the literature.粒细胞肉瘤:32例病例及文献复习
Leuk Lymphoma. 2006 Dec;47(12):2527-41. doi: 10.1080/10428190600967196.
2
Clinico-pathological characteristics of myeloid sarcoma at diagnosis and during follow-up: report of 12 cases from a single institution.髓系肉瘤诊断及随访期间的临床病理特征:来自单一机构的12例报告
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Nonleukemic granulocytic sarcoma of knee: a case report.膝关节非白血病性粒细胞肉瘤:一例报告
Case Rep Med. 2010;2010:235295. doi: 10.1155/2010/235295. Epub 2010 Dec 14.
接受化疗联合或不联合放疗的非白血病性粒细胞肉瘤患者的治疗结果。
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Isolated granulocytic sarcoma of the humerus.孤立性肱骨粒细胞肉瘤
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Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases.粒细胞肉瘤:61例活检病例的临床病理研究
Cancer. 1981 Sep 15;48(6):1426-37. doi: 10.1002/1097-0142(19810915)48:6<1426::aid-cncr2820480626>3.0.co;2-g.