肠炎沙门氏菌维乔血清型中与沙门氏菌基因组岛1的复合整合子相邻的截短tni模块。
Truncated tni module adjacent to the complex integron of salmonella genomic island 1 in Salmonella enterica serovar Virchow.
作者信息
Doublet Benoît, Chu Chishih, Chiu Cheng-Hsun, Fan Yi-Chin, Cloeckaert Axel
机构信息
Infectiologie Animale et Santé Publique, Nouzilly, France.
出版信息
Antimicrob Agents Chemother. 2009 Feb;53(2):824-7. doi: 10.1128/AAC.01015-08. Epub 2008 Nov 17.
Abstract
Salmonella genomic island 1 was identified for the first time in Salmonella enterica serovar Virchow isolated from humans in Taiwan. The complex class 1 integron conferring multidrug resistance was shown to be inserted within open reading frame (ORF) S023 and contains for the first time a partial transpositional module. The 5-bp target duplication flanking the complex integron suggests that its insertion in ORF S023 was by transposition.
摘要
首次在从台湾人类分离出的肠炎沙门氏菌维氏血清型中鉴定出沙门氏菌基因组岛1。赋予多重耐药性的复杂1类整合子被证明插入在开放阅读框（ORF）S023内，并且首次包含一个部分转座模块。复杂整合子两侧的5碱基对靶标重复表明其在ORF S023中的插入是通过转座作用。
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