原发性血管肉瘤导致脾破裂：一例病例报告

Spleen rupture due to primary angiosarcoma: a case report.

作者信息

Koutelidakis Ioannis M, Tsiaousis Panagiotis Z, Papaziogas Basilios Th, Patsas Aristeides G, Atmatzidis Stefanos K, Atmatzidis Konstantinos S

机构信息

2nd Department of Surgery, Aristoteles University of Thessaloniki, G. Gennimatas General Hospital, Thessaloniki, Greece.

出版信息

J Gastrointest Cancer. 2007;38(2-4):74-7. doi: 10.1007/s12029-008-9034-y. Epub 2008 Nov 19.

DOI:10.1007/s12029-008-9034-y

PMID:19016352

Abstract

A case of a 79-year-old female with rupture of the spleen due to primary angiosarcoma is presented. Symptoms were non-specific. Diagnosis was based on histology postoperatively. Primary angiosarcoma of the spleen is a very rare and aggressive neoplasm with a high metastatic rate and almost uniformly fatal. Due to small number of reported cases, there are no guidelines concerning adjuvant or palliative treatment or any beneficial protocols of chemotherapy or radiotherapy up to date. Splenectomy prior to rupture seems to have a positive impact on long-term survival.

摘要

本文报告一例79岁女性因原发性血管肉瘤导致脾破裂的病例。症状不具有特异性。诊断基于术后组织学检查。脾脏原发性血管肉瘤是一种非常罕见且侵袭性强的肿瘤，转移率高，几乎无一例外会导致死亡。由于报告的病例数量较少，目前尚无关于辅助治疗或姑息治疗的指南，也没有任何有效的化疗或放疗方案。在脾破裂前进行脾切除术似乎对长期生存有积极影响。