Suppr超能文献

拔毛癖患儿的抑郁、焦虑及功能损害

Depression, anxiety, and functional impairment in children with trichotillomania.

作者信息

Lewin Adam B, Piacentini John, Flessner Christopher A, Woods Douglas W, Franklin Martin E, Keuthen Nancy J, Moore Phoebe, Khanna Muniya, March John S, Stein Dan J

机构信息

UCLA Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, Los Angeles, CA 90024-1759, USA.

出版信息

Depress Anxiety. 2009;26(6):521-7. doi: 10.1002/da.20537.

Abstract

BACKGROUND

Trichotillomania (TTM) remains understudied in children. Adult research suggests that TTM is accompanied by significant depression, anxiety, and functional impairment. The purpose of this study is to examine the occurrence of depression and anxiety in a relatively large sample of youth with TTM and the extent to which these symptoms mediate the relationship between TTM severity and associated impairment.

METHODS

The study utilized data from the Child and Adolescent Trichotillomania Impact Project (CA-TIP), an internet-based sample of 133 youth aged 10-17 (inclusive) with TTM.

RESULTS

Over 45% of children with TTM endorsed depressive symptoms and 40% endorsed anxiety symptoms in excess of one standard deviation (SD) above published community norms. More remarkably, 25% of our sample reported depressive and 20% reported anxiety symptoms in excess of 2 SD above these norms. Older participants reported more symptoms of depression and anxiety than younger ones; age of onset (children with later onset), but not duration of illness, was predictive of higher reports of both depressive and anxiety symptoms. Neither depressive nor anxiety symptoms were related to pulling site. Depressive symptoms partially mediated the relationship between TTM severity and functional impairment.

CONCLUSIONS

Based on an internet sample recruited from the homepage of the Trichotillomania Learning Center, data from this study suggests that symptoms of depression and anxiety may be pervasive among youth with TTM and likely impact functional impairment. Longitudinal studies using directly assessed samples are needed to replicate and extend these findings.

摘要

背景

儿童拔毛癖(TTM)的研究仍较少。成人研究表明,拔毛癖伴有严重的抑郁、焦虑和功能损害。本研究的目的是调查在一个相对较大的患有拔毛癖的青少年样本中抑郁和焦虑的发生率,以及这些症状在多大程度上介导了拔毛癖严重程度与相关损害之间的关系。

方法

本研究使用了来自儿童和青少年拔毛癖影响项目(CA-TIP)的数据,该项目是一个基于网络的样本,包含133名年龄在10 - 17岁(含)的患有拔毛癖的青少年。

结果

超过45%的患有拔毛癖的儿童认可存在抑郁症状,40%认可存在焦虑症状,且这些症状超过已发表的社区常模一个标准差(SD)以上。更值得注意的是,我们样本中有25%报告存在超过这些常模两个标准差以上的抑郁症状,20%报告存在超过这些常模两个标准差以上的焦虑症状。年龄较大的参与者报告的抑郁和焦虑症状比年龄较小的参与者更多;起病年龄(起病较晚的儿童)而非病程,可预测更高的抑郁和焦虑症状报告。抑郁症状和焦虑症状均与拔毛部位无关。抑郁症状部分介导了拔毛癖严重程度与功能损害之间的关系。

结论

基于从拔毛癖学习中心主页招募的网络样本,本研究数据表明,抑郁和焦虑症状在患有拔毛癖的青少年中可能普遍存在,并可能影响功能损害。需要使用直接评估样本的纵向研究来重复和扩展这些发现。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验