Gough Nancy R
Sci Signal. 2008 Nov 18;1(46):eg8. doi: 10.1126/scisignal.146eg8.
The complexity of the signaling network that is initiated by members of the transforming growth factor-beta (TGF-beta) superfamily continues to increase. In addition, Smads, which were originally identified as key transducers of TGF-beta signals, are beginning to emerge as players in other TGF-beta-independent processes. Perspectives in this issue, as well as highlights from a recent meeting on TGF-beta and select resources from the Archives, spotlight this emerging complexity.
由转化生长因子-β（TGF-β）超家族成员引发的信号网络的复杂性持续增加。此外，最初被确定为TGF-β信号关键转导因子的Smads，开始在其他与TGF-β无关的过程中发挥作用。本期的观点以及最近一次关于TGF-β会议的要点和来自档案馆的精选资源，都聚焦于这种新出现的复杂性。
