Pasquet F, Pavic M, Estival J-L, Karkowski L, Debourdeau P
Service de médecine interne-oncologie, hôpital d'instruction-des-armées Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
Rev Med Interne. 2009 Jul;30(7):637-9. doi: 10.1016/j.revmed.2008.09.015. Epub 2008 Nov 18.
Bleomycin is a cytotoxic agent used in the treatment of various neoplasias. Its cutaneous adverse effects are diverse. Some of them are rare but specific. We report the case of a 40-year-old man presenting with a non-seminomatous testicular germ cell tumour who developed a flagellate erythema related to a bleomycin administration. Clinical features, histopathology and disease course are presented. This side effect is apparently neither related to the dose nor to the mode of administration of bleomycin. The etiopathogenic mechanism remains unknown.
