患有生殖器鳞状上皮内病变的女性中肛门鳞状上皮内病变的患病率。
Prevalence of anal squamous intra-epithelial lesion in women presenting genital squamous intra-epithelial lesion.
作者信息
Giraldo Paulo, Jacyntho Cláudia, Costa Cristina, Iglesias Maruccia, Gondim Consuelo, Carvalho Francisca, Giraldo Helena, Gonçalves Ana Katherine
机构信息
Department of Gynecology and Obstetrics, University of Campinas, SP, Brazil.
出版信息
Eur J Obstet Gynecol Reprod Biol. 2009 Jan;142(1):73-5. doi: 10.1016/j.ejogrb.2008.09.014. Epub 2008 Nov 18.
OBJECTIVE
To determine the frequency of anal squamous intra-epithelial lesions (ASIL) in women with genital squamous intra-epithelial lesions (GSIL).
STUDY DESIGN
In a cross sectional study, 184 patients with histopathological diagnosis of GSIL and 76 controls without GSIL, were submitted to anuscopy in order to determine the presence of ASIL. All the women were HIV-negative with anal aceto-white lesions were biopsed for histological diagnosis.
RESULTS
The frequency of ASIL was 17.4% in the GSIL group (3.2% high grade ASIL) and only 2.6% in the control group (0% high grade ASIL) (p<0.001). All the high grade ASIL diagnoses were found in women with cervical SIL.
CONCLUSION
Women presenting GSIL have high prevalence of ASIL.
目的
确定患有生殖器鳞状上皮内病变（GSIL）的女性中肛门鳞状上皮内病变（ASIL）的发生率。
研究设计
在一项横断面研究中，184例经组织病理学诊断为GSIL的患者和76例无GSIL的对照者接受了肛门镜检查，以确定ASIL的存在。所有女性均为HIV阴性，对有肛门醋酸白病变的患者进行活检以进行组织学诊断。
结果
GSIL组中ASIL的发生率为17.4%（高级别ASIL为3.2%），而对照组中仅为2.6%（高级别ASIL为0%）（p<0.001）。所有高级别ASIL诊断均见于患有宫颈上皮内瘤变（SIL）的女性。
结论
患有GSIL的女性中ASIL的患病率较高。
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