Shah Bijal M, Gupchup Gireesh V, Borrego Matthew E, Raisch Dennis W, Knapp Katherine K
College of Pharmacy, Touro University, Vallejo, CA 94592, USA.
J Am Pharm Assoc (2003). 2008 Nov-Dec;48(6):737-43. doi: 10.1331/JAPhA.2008.07078.
To assess the frequency of untreated, self-reported depressive symptoms in a cross section of adult ambulatory patients with type 2 diabetes and to identify demographic and/or clinical characteristics associated with depressive symptoms in study patients.
Cross-sectional study.
Three ambulatory care clinics in the southwestern United States in fall 2005.
217 primary care patients aged 18 years or older with a diagnosis of type 2 diabetes.
Administration of the Zung Self-rating Depression Scale (Zung SDS).
Self-reported data on demographic characteristics and depressive symptoms. Data for insurance, comorbid conditions, and glycosylated hemoglobin (A1C) values were abstracted from patient charts.
Depressive symptoms (Zung SDS score > or =50) were identified in 72.1% of patients. Overall, 13% of the patients with a diagnosis of depression (based on patient charts) were not receiving treatment. Factors significantly associated with depressive symptoms were past history of depression (beta= 0.53, P < 0.01), Medicaid insurance (beta= 0.15, P < 0.02), and insulin use (beta= 0.12, P < 0.05).
The results suggest that possible undetected or untreated depression can be assessed in patients with type 2 diabetes through use of a self-rating scale in the course of routine ambulatory care. Adding the Zung SDS screen to routine care protocols could facilitate improved detection and treatment of comorbid depression in ambulatory patients with type 2 diabetes.
评估2型糖尿病成年门诊患者中未经治疗的、自我报告的抑郁症状的发生率,并确定与研究患者抑郁症状相关的人口统计学和/或临床特征。
横断面研究。
2005年秋季美国西南部的三家门诊护理诊所。
217名年龄在18岁及以上、诊断为2型糖尿病的初级护理患者。
采用zung自评抑郁量表(zung SDS)进行评估。
自我报告的人口统计学特征和抑郁症状数据。保险、合并症和糖化血红蛋白(A1C)值的数据从患者病历中提取。
72.1%的患者存在抑郁症状(zung SDS评分≥50)。总体而言,13%诊断为抑郁症的患者(基于患者病历)未接受治疗。与抑郁症状显著相关的因素有抑郁症病史(β=0.53,P<0.01)、医疗补助保险(β=0.15,P<0.02)和胰岛素使用(β=0.12,P<0.05)。
结果表明,在常规门诊护理过程中,通过使用自评量表可以评估2型糖尿病患者中可能未被发现或未得到治疗的抑郁症。在常规护理方案中增加zung SDS筛查可以促进改善对2型糖尿病门诊患者合并抑郁症的检测和治疗。