Sparrapan Regina, Eberlin Marcos N, Alberici Rosana M
ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas - UNICAMP, 13083-970, Campinas, SP, Brazil.
Rapid Commun Mass Spectrom. 2008 Dec;22(24):4105-8. doi: 10.1002/rcm.3830.
Trap-and-release membrane introduction mass spectrometry (T&R-MIMS) with a removable direct insertion membrane probe (DIMP) is used to quantitate a variety of trace phenolic compounds in water after acetylation. The procedure is simple, rapid and robust, producing linear and reproducible responses for phenolic compounds with varying polarities. Acetylation minimizes the polarity effects of ring substituents; hence, T&R-MIMS of the acetylated phenols provides lower and more uniform limits of detection (LODs) (2-15 microg L(-1)) than those obtained by direct T&R-MIMS analysis of the non-derivatized phenols.
采用带有可移除直接插入式膜探针（DIMP）的捕集-释放膜引入质谱法（T&R-MIMS）对乙酰化后的水中多种痕量酚类化合物进行定量分析。该方法简单、快速且稳定，对不同极性的酚类化合物能产生线性且可重复的响应。乙酰化可使环取代基的极性效应降至最低；因此，与通过直接T&R-MIMS分析未衍生化酚类相比，乙酰化酚类的T&R-MIMS提供了更低且更均匀的检测限（LOD）（2 - 15 μg L⁻¹）。
