Audebert Heinrich J, Schultes Kathrin, Tietz Viola, Heuschmann Peter U, Bogdahn Ulrich, Haberl Roman L, Schenkel Johannes
Stroke Unit, Department of Ageing and Health, Guy's and St Thomas' NHS Foundation Trust, King's, Guy's and St Thomas' Medical School, London, UK.
Stroke. 2009 Mar;40(3):902-8. doi: 10.1161/STROKEAHA.108.529255. Epub 2008 Nov 20.
Stroke unit treatment is effective in reducing death and dependency after stroke but is not available in many, particularly rural, areas. The implementation of a stroke network with telemedicine support was associated with improved outcome at 3 months. We report follow-up results at 12 and 30 months after acute stroke.
Telemedical Project for Integrative Stroke Care (TEMPiS) consists of the set-up of specialized local stroke wards, continuous medical education, and telemedical consultation for patients with acute stroke by 2 stroke centers. In a prospective, nonrandomized, intervention study, 5 community hospitals participating in the network were compared with 5 matched control hospitals without specialized stroke facilities or telemedical support. All patients with consecutive ischemic or hemorrhagic stroke admitted between July 2003 and March 2005 were evaluated. Outcome "death and dependency" was defined by death, institutional care, or disability (Barthel index <60 or Rankin scale >3).
We followed-up 3060 patients (1938 in TEMPiS and 1122 in control hospitals). Follow-up rates were 97.2% after 12 months and 95.9% after 30 months for death or institutional care, and 96.5% after 12 months and 95.7% after 30 months for death and dependency. In multivariable regression analysis, there was no significant effect of the TEMPiS intervention for reduced "death or institutional care" at 12 months (OR, 0.89; 95% CI, 0.75-1.07; P=0.23) and 30 months (OR, 0.93; 95% CI, 0.78-1.11; P=0.40) but a significant reduction of "death and dependency" at 12 months (OR, 0.65; 95% CI, 0.54-0.78; P<0.01) and 30 months (OR, 0.82; 95% CI, 0.68-0.98; P=0.031).
Implementing a system of specialized stroke wards, continuing education, and telemedicine in community hospitals offers long-term benefit for acute stroke patients.
卒中单元治疗在降低卒中后的死亡率和依赖性方面有效,但在许多地区,尤其是农村地区无法提供。实施一个有远程医疗支持的卒中网络与3个月时改善的预后相关。我们报告急性卒中后12个月和30个月的随访结果。
综合卒中治疗远程医疗项目(TEMPiS)包括设立专门的当地卒中病房、持续医学教育以及由2个卒中中心对急性卒中患者进行远程医疗会诊。在一项前瞻性、非随机干预研究中,将参与该网络的5家社区医院与5家匹配的无专门卒中设施或远程医疗支持的对照医院进行比较。对2003年7月至2005年3月期间收治的所有连续性缺血性或出血性卒中患者进行评估。结局“死亡和依赖性”定义为死亡、机构护理或残疾(Barthel指数<60或Rankin量表>3)。
我们对3060例患者进行了随访(TEMPiS组1938例,对照医院组1122例)。死亡或机构护理的12个月随访率为97.2%,30个月随访率为95.9%;死亡和依赖性的12个月随访率为96.5%,30个月随访率为95.7%。在多变量回归分析中,TEMPiS干预在12个月(比值比,0.89;95%置信区间为0.75 - 1.07;P = 0.23)和30个月(比值比,0.93;95%置信区间为0.78 - 1.11;P = 0.40)时对降低“死亡或机构护理”无显著影响,但在12个月(比值比,0.65;95%置信区间为0.54 - 0.78;P < 0.01)和30个月(比值比,0.82;95%置信区间为0.68 - 0.98;P = 0.031)时对降低“死亡和依赖性”有显著效果。
在社区医院实施专门的卒中病房、继续教育和远程医疗系统可为急性卒中患者带来长期益处。