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一名儿童的后颅窝透明细胞型脑膜瘤,无硬脑膜附着。

Posterior fossa clear cell meningioma without dural attachment in a child.

作者信息

Miranda Pablo, Simal Juan Antonio, Vila Manuel, Hernández Miguel, Menor Francisco, Alvarez-Garijo José Andrés

机构信息

Department of Neurosurgery, Division of Pediatric Neurosurgery, Hospital Universitario Infantil La Fe, Avda Campanar s/n., 46009 Valencia, Spain.

出版信息

Childs Nerv Syst. 2009 Mar;25(3):389-92. doi: 10.1007/s00381-008-0757-7. Epub 2008 Nov 22.

Abstract

INTRODUCTION

Meningiomas are relatively uncommon in childhood. They represent 1% to 2% of all intracranial tumours of infancy and childhood and 1.5% to 1.8% of all intracranial meningiomas. Occasionally, meningiomas may develop without dural attachment. Clear cell meningioma is a histological distinctive uncommon variant of meningioma that may behave aggressively with local recurrence and progression as well as cerebrospinal fluid-borne metastasis. Meningiomas near the craniocervical junction represent challenging tumours, requiring special considerations because of the vicinity of the medulla oblongata, the lower cranial nerves and the vertebral artery.

CASE REPORT

In this study, the authors present a rare case of posterior fossa clear cell meningioma without dural attachment in a child with severe brainstem and cervical spinal cord displacement and discuss the clinical and radiological features as well as treatment considerations.

摘要

引言

脑膜瘤在儿童期相对少见。它们占婴儿期和儿童期所有颅内肿瘤的1%至2%,占所有颅内脑膜瘤的1.5%至1.8%。偶尔,脑膜瘤可能在没有硬膜附着的情况下发生。透明细胞脑膜瘤是脑膜瘤的一种组织学上独特的罕见变体,可能具有侵袭性,会出现局部复发和进展以及脑脊液播散转移。颅颈交界处附近的脑膜瘤是具有挑战性的肿瘤,由于延髓、低位颅神经和椎动脉位置临近,需要特殊考虑。

病例报告

在本研究中,作者报告了1例罕见的儿童后颅窝透明细胞脑膜瘤,该肿瘤无硬膜附着,伴有严重的脑干和颈脊髓移位,并讨论了其临床和放射学特征以及治疗考量。

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