从延胡索中分离得到的两种新的原小檗碱季铵生物碱。

Two new protoberberine quaternary alkaloids from Corydalis yanhusuo.

作者信息

Cheng Xing-Ye, Shi Yue, Zheng Shun-Liang, Jin Wen, Sun Hong

机构信息

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1117-21. doi: 10.1080/10286020802410615.

DOI:10.1080/10286020802410615

PMID:19031256

Abstract

Two new protoberberine quaternary alkaloids, 13-methyl-palmatrubine (1) and 13-methyl-dehydrocorydalmine (2), were isolated from the tubers of Corydalis yanhusuo W.T. Wang. 1 was isolated as a natural product for the first time, and 2 a new compound. Their structures were elucidated on the basis of spectroscopic evidence, especially 1D- and 2D-NMR experiments.

摘要

从延胡索（Corydalis yanhusuo W.T. Wang）块茎中分离得到两种新的原小檗碱季铵生物碱，13-甲基巴马亭（1）和13-甲基脱氢紫堇碱（2）。1为首次作为天然产物分离得到，2为新化合物。基于光谱证据，尤其是一维和二维核磁共振实验对它们的结构进行了阐明。