Cox Brian J, Pagura Jina, Stein Murray B, Sareen Jitender
Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada.
Depress Anxiety. 2009;26(4):354-62. doi: 10.1002/da.20475.
There has been ongoing clinical controversy dating back to the revised third edition of the Diagnostic and Statistical Manual of Mental Disorders concerning the boundaries and extent of overlap between Axis I generalized social phobia (GSP) and Axis II avoidant personality disorder (APD). This study sought to examine the relationship between the fourth edition of Diagnostic and Statistical Manual of Mental Disorders GSP and APD in a large nationally representative sample of the United States population.
We used the National Epidemiologic Survey on Alcohol and Related Conditions (n=43,093; age 18+; response rate=81%) to study fourth edition of Diagnostic and Statistical Manual of Mental Disorders Axes I and II psychiatric disorders, assessed by a reliable semi-structured in-person interview.
The lifetime prevalence was 2.8% for GSP and 2.4% for APD. The overlap between GSP and APD varied according to the number of GSP social situations feared. Although 36.4% of individuals with GSP were diagnosed with APD, the majority (57.3%) of individuals with GSP who feared all 13 social situations assessed were diagnosed with APD. Nearly 40% of individuals with APD also had GSP. Compared to individuals with GSP alone, individuals with comorbid GSP and APD showed significantly lower mental health-related quality of life on the Medical Outcomes Study Short Form, more interaction and observation fears, and an increased likelihood of having other psychiatric disorders such as major depression.
APD and GSP show a high degree of overlap (16-57%), depending on the number of social situations feared. Overall, results suggest that APD and GSP appear to be highly related, but potentially separable constructs. Further research is needed to identify the determinants and consequences of having either or both diagnoses.
自《精神疾病诊断与统计手册》第三版修订本以来,关于轴I广泛性社交恐惧症(GSP)与轴II回避型人格障碍(APD)之间的界限及重叠程度一直存在临床争议。本研究旨在在美国具有全国代表性的大样本中,考察《精神疾病诊断与统计手册》第四版中GSP与APD之间的关系。
我们利用全国酒精及相关状况流行病学调查(n = 43093;年龄18岁及以上;应答率 = 81%),通过可靠的半结构化面对面访谈来研究《精神疾病诊断与统计手册》第四版中轴I和轴II精神障碍。
GSP的终生患病率为2.8%,APD为2.4%。GSP与APD的重叠程度因所恐惧的GSP社交情境数量而异。虽然36.4%的GSP患者被诊断为APD,但在评估的13种社交情境中恐惧所有情境的GSP患者中,大多数(57.3%)被诊断为APD。近40%的APD患者也患有GSP。与单纯患有GSP的个体相比,合并GSP和APD的个体在医学结果研究简表上的心理健康相关生活质量显著更低,有更多的互动和观察恐惧,并且患其他精神障碍如重度抑郁症的可能性增加。
APD和GSP显示出高度重叠(16 - 57%),具体取决于所恐惧的社交情境数量。总体而言,结果表明APD和GSP似乎高度相关,但可能是可分离的结构。需要进一步研究以确定患有其中一种或两种诊断的决定因素和后果。