Devineni V R, Hayden R, Fredrickson J, Sicard G
Radiation Oncology Center, Washington University Medical Center, St. Louis, MO 63110.
Laryngoscope. 1991 May;101(5):462-4. doi: 10.1288/00005537-199105000-00002.
When malignant lesions of the oral cavity, base of tongue, and oropharynx are treated with radical resection, adequate reconstruction is required. The free gastric mucosal flap with microvascular transfer is being used with increasing frequency at Washington University Medical Center. Because of the advanced nature of the primary lesions, most patients also require postoperative radiation therapy. In this paper the tolerance of the gastric mucosal flap to postoperative radiation therapy is reviewed. The changes resulting from radiation therapy in the mucosal flap were found to be acceptable, and no major complications were encountered.
当口腔、舌根和口咽的恶性病变采用根治性切除治疗时，需要进行充分的重建。华盛顿大学医学中心越来越频繁地使用带微血管转移的游离胃黏膜瓣。由于原发性病变的进展性质，大多数患者还需要术后放疗。本文回顾了胃黏膜瓣对术后放疗的耐受性。发现放疗引起的黏膜瓣变化是可以接受的，且未出现重大并发症。
