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继发于左心室收缩功能障碍的肺动脉高压:当代诊断与管理

Pulmonary hypertension secondary to left ventricular systolic dysfunction: contemporary diagnosis and management.

作者信息

Shah Ravi V, Semigran Marc J

机构信息

Department of Medicine, Massachusetts General Hospital, Grey Bigelow 8, 55 Fruit Street, Boston, MA 02114, USA.

出版信息

Curr Heart Fail Rep. 2008 Dec;5(4):226-32. doi: 10.1007/s11897-008-0034-9.

Abstract

Pulmonary hypertension secondary to left ventricular systolic dysfunction is often a poor prognostic marker in chronic heart failure. In this article, we review evidence supporting modern strategies addressing pulmonary hypertension in patients with left ventricular systolic dysfunction, including right-sided heart catheterization with vasoreactivity testing and subsequent parenteral, oral, and inhaled therapy. We delineate a diagnostic approach to secondary pulmonary hypertension and outline evidence-based therapeutic strategies for management in acute and chronic heart failure.

摘要

继发于左心室收缩功能障碍的肺动脉高压通常是慢性心力衰竭预后不良的标志。在本文中,我们回顾了支持针对左心室收缩功能障碍患者肺动脉高压的现代治疗策略的证据,包括进行血管反应性测试的右心导管检查以及随后的肠外、口服和吸入治疗。我们阐述了继发性肺动脉高压的诊断方法,并概述了急性和慢性心力衰竭管理的循证治疗策略。

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