Ushio Munetaka, Iwasaki Shinichi, Chihara Yasuhiro, Kawahara Nobutaka, Morita Akio, Saito Nobuhito, Murofushi Toshihisa
Department of Otolaryngology, Graduate School of Medicine, University of Tokyo, Tokyo.
Acta Otolaryngol. 2009 Oct;129(10):1095-100. doi: 10.1080/00016480802552543.
The results of the caloric test, vestibular evoked myogenic potential (VEMP), and auditory brainstem response (ABR) in patients with vestibular schwannoma (VS) did not show clear correlation with the nerve origin of the tumor but with tumor size. When we focused on patients with VS within the internal acoustic canal (IAC), neither the nerve origin of the tumor nor the tumor size showed clear correlation with the results of these tests.
This study examined the correlation of the nerve origin of VS, superior or inferior vestibular nerve, with the results of function tests.
Subjects comprised 109 consecutive patients diagnosed as having unilateral VS. Each test was performed before surgery. Tumor size was measured with preoperative MRI.
The nerve origin of the tumor was identified in 63 of the 109 patients. The percentage of patients showing abnormal responses in each test was not different between 37 patients with superior VS and 26 patients with inferior VS. Also, no difference was observed for patients with VS within the IAC. Mean tumor size in patients showing abnormal responses was larger than that in patients showing normal responses on each test. However, this tendency was not observed for patients with VS within the IAC.
前庭神经鞘瘤（VS）患者的冷热试验、前庭诱发肌源性电位（VEMP）和听性脑干反应（ABR）结果与肿瘤的神经起源无明显相关性，而是与肿瘤大小相关。当我们关注内耳道（IAC）内VS患者时，肿瘤的神经起源和肿瘤大小与这些检查结果均无明显相关性。
本研究探讨VS的神经起源（前庭上神经或前庭下神经）与功能检查结果的相关性。
研究对象为109例连续诊断为单侧VS的患者。每项检查均在手术前进行。术前通过MRI测量肿瘤大小。
109例患者中有63例确定了肿瘤的神经起源。37例前庭上神经起源的VS患者和26例前庭下神经起源的VS患者在每项检查中出现异常反应的患者百分比无差异。IAC内VS患者也未观察到差异。每项检查中出现异常反应的患者的平均肿瘤大小大于反应正常的患者。然而，IAC内VS患者未观察到这种趋势。
