Guo Jian-Chao, Zheng Shao-Xiong, Li Xiao-Dong, Zhang Zun-Cheng, Bi Zheng-Zheng, Zhang Jian-Hua
Department of Endocrinology, The Second Hospital, Tianjin Medical University, Tianjin 300211, China.
Zhonghua Nei Ke Za Zhi. 2008 Jul;47(7):560-2.
To evaluate the early detection of diabetic cystopathy (DCP) with the technology of noninvasive urodynamics.
70 patients with type 2 diabetes mellitus (DM) and 30 normal control subjects were checked with the technology of noninvasive urodynamics. Based on their disease course of less or more than 5 years, the DM patients were divided into two groups. Maximal flow rate, average flow rate, the volume leading to first bladder sensation and residual urine volume were measured by using noninvasive urodynamic technology.
Among the 70 DM patients, 34 were detected to have bladder residual urine, so the DCP detection rate was 48.6%. In the patients with DCP, the average residual urine volume was 7-139 ml (30.1 +/- 27.1) ml, while there was no residual urine in the normal control group. As compared with the normal control group, maximal flow rate and average flow rate were decreased in all the patients with DM and those with DCP (P < 0.01). After follow up of the disease, the patients with a course of more than five years of disease control had even lower maximal flow rate and average flow rate.
Maximal flow rate decrease and bladder residual urine detected with the technology of noninvasive urodynamics may be widely used in early detection and early diagnosis of DCP.
运用无创尿动力学技术评估糖尿病膀胱病变(DCP)的早期检测情况。
对70例2型糖尿病(DM)患者和30例正常对照者采用无创尿动力学技术进行检查。根据DM患者病程是否超过5年将其分为两组。运用无创尿动力学技术测量最大尿流率、平均尿流率、首次膀胱感觉容量及残余尿量。
70例DM患者中,检测出34例存在膀胱残余尿,DCP检出率为48.6%。DCP患者平均残余尿量为7 - 139 ml(30.1±27.1)ml,而正常对照组无残余尿。与正常对照组相比,所有DM患者及DCP患者的最大尿流率和平均尿流率均降低(P<0.01)。对病情进行随访后,病程超过5年且病情得到控制的患者最大尿流率和平均尿流率更低。
无创尿动力学技术检测到的最大尿流率降低及膀胱残余尿可能广泛应用于DCP的早期检测和早期诊断。