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肺结核合并支气管内膜结核的外科治疗

[Surgical treatment of pulmonary tuberculosis combined with endobronchial tuberculosis].

作者信息

Yang Jian, Jiang Ge-Ning, Ding Jia-An, Tong Wen-Pu

机构信息

Department of Thoracic Surgery, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2008 Jul 1;46(13):992-4.

Abstract

OBJECTIVE

To evaluate the experience of surgical treatment of pulmonary tuberculosis with endobronchial tuberculosis.

METHODS

The clinical data of 85 patients with pulmonary tuberculosis and endobronchial tuberculosis undergoing surgical resection from 1967 to 2004 were reviewed retrospectively. Forty-five cases were bronchial stenosis. Four cases were tracheal stenosis. Sixteen cases underwent right upper lobectomy. One case underwent right upper and middle lobectomy. Three cases underwent right middle lobectomy. Five cases underwent right middle and lower lobectomy. Two cases underwent right lower lobectomy. Twelve cases underwent left upper lobectomy. Four cases underwent left lower lobectomy. Eight cases were assisted with sleeve lobectomy. Six cases underwent right pneumonectomy (with partial tracheal resection and tracheal reconstruction in 3 cases). Thirty cases underwent left pneumonectomy. One case underwent left lower lobectomy who underwent left upper lobectomy 2 years ago. Four cases were assisted with sleeve pneumonectomy. Three cases underwent tracheal segment resection and tracheal reconstruction. One case underwent left upper bronchial and pulmonary artery sleeve resection. One case underwent biopsy.

RESULTS

No surgical mortality occurred. There was 1 case of bronchopleural fistula and 1 case of empyema in the 35 cases (without sleeve lobectomy) who underwent lobectomy. There were 3 cases of bronchopleural fistula and 4 cases of empyema in the 33 cases (without sleeve pneumonectomy) who underwent pneumonectomy (P < 0.05). There were 5 cases of atelectasis in the 35 cases who underwent lobectomy and 3 cases of atelectasis in the 8 cases who underwent sleeve lobectomy (P < 0.01). In the follow-up of 3 to 10 years, 1 case died due to acute respiratory distress syndrome 7 years postoperatively.

CONCLUSIONS

It is important to resect all the tissue which has been infected. With the routine anti-tuberculosis chemotherapy during the perioperative period, the effect of surgical treatment is superior to others. Fewer pneumonectomy is also important.

摘要

目的

评估合并支气管内膜结核的肺结核手术治疗经验。

方法

回顾性分析1967年至2004年85例接受手术切除的合并支气管内膜结核的肺结核患者的临床资料。45例为支气管狭窄。4例为气管狭窄。16例行右上叶切除术。1例行右肺上中叶切除术。3例行右中叶切除术。5例行右肺中、下叶切除术。2例行右下叶切除术。12例行左上叶切除术。4例行左下叶切除术。8例辅助袖状肺叶切除术。6例行右全肺切除术(3例同时行部分气管切除及气管重建)。30例行左全肺切除术。1例曾于2年前行左上叶切除术,此次行左下叶切除术。4例辅助袖状全肺切除术。3例行气管段切除及气管重建。1例行左上支气管及肺动脉袖状切除。1例行活检。

结果

无手术死亡病例。在35例(未行袖状肺叶切除术)行肺叶切除术的患者中,有1例发生支气管胸膜瘘,1例发生脓胸。在33例(未行袖状全肺切除术)行全肺切除术的患者中,有3例发生支气管胸膜瘘,4例发生脓胸(P<0.05)。在35例行肺叶切除术的患者中有5例发生肺不张,在8例行袖状肺叶切除术的患者中有3例发生肺不张(P<0.01)。在3至10年的随访中,1例患者术后7年因急性呼吸窘迫综合征死亡。

结论

切除所有感染组织很重要。围手术期进行常规抗结核化疗,手术治疗效果优于其他治疗。减少全肺切除术也很重要。

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