Ren Zhe, Liang Qing-feng, Guo Sheng, Zhou Yu-mei, Li Ran, Sun Xu-guang
Beijing Institute of Ophthalmology, Beijing Tongren Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100005, China.
Zhonghua Yan Ke Za Zhi. 2008 Jun;44(6):507-10.
To assess the prevalence and risk factors for trachoma among primary school children in Datong City, China.
An epidemiological survey was carried out in Datong City in 2006. Children aged 6 to 14 years old in primary school were selected by a cluster sampling in which class shift was the sampling unit. Trachoma was clinically assessed according to the simplified classification for trachoma proposed by the World Health Organization (WHO). If the child was clinically diagnosed as trachoma, a conjunctival swab would be taken for detecting C. trachomatis by antigen test and polymerase chain reaction (PCR).
A total of 1236 children were examined and 135 cases of trachoma were found, the prevalence of trachoma was 10.9% (95% CI: 9.2% - 12.6%). Follicular trachoma was found in 86.7% of the cases and intense trachoma in 13.3%. The overall prevalence of trachoma was higher for females than for males (13.1% versus 8.8%, P = 0.016). Thirteen (9.6%) cases were positive in C. trachomatis antigen test, and 86 (63.7%) cases were positive by PCR. Poor ocular hygiene and sharing wash cloth and face basin with households were the main risk factors.
Trachoma is endemic among primary school children in Datong City in China.
评估中国大同市小学生沙眼的患病率及危险因素。
2006年在大同市开展了一项流行病学调查。以班级为抽样单位,采用整群抽样的方法选取6至14岁的小学生。根据世界卫生组织(WHO)提出的沙眼简化分类标准对沙眼进行临床评估。如果儿童被临床诊断为沙眼,则采集结膜拭子,通过抗原检测和聚合酶链反应(PCR)检测沙眼衣原体。
共检查了1236名儿童,发现135例沙眼病例,沙眼患病率为10.9%(95%可信区间:9.2% - 12.6%)。86.7%的病例为滤泡性沙眼,13.3%为重度沙眼。女性沙眼总体患病率高于男性(13.1%对8.8%,P = 0.016)。13例(9.6%)沙眼衣原体抗原检测呈阳性,86例(63.7%)PCR检测呈阳性。眼部卫生差以及与家人共用毛巾和脸盆是主要危险因素。
沙眼在中国大同市小学生中呈地方性流行。