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[1例接受全身皮肤电子束照射治疗的急性单核细胞白血病皮肤浸润病例]

[A case of acute monocytic leukemia cutis treated with total skin electron beam irradiation].

作者信息

Kawazoe E, Fukurono K, Onizuka Y, Joh S, Akeda N, Ohtake H

机构信息

Department of Radiology, Kurume University School of Medicine.

出版信息

Nihon Igaku Hoshasen Gakkai Zasshi. 1991 Feb 25;51(2):162-7.

PMID:1903528
Abstract

A 35-year-old man with acute monocytic leukemia (AMoL) cutis was treated with total skin electron beam irradiation (TSEBI), because the widespread skin infiltration of AMoL appeared after induction chemotherapy. A skin nodule was authenticated as leukemic cell by biopsy. The patient was irradiated 4 times a week with 200 cGy per fraction to a total dose of 1200 cGy, using 6 MeV electrons from 8 directions. The therapy was accomplished separately on the upper and lower halves of the body. Focus-skin distance was 310 cm. An acrylic plate applicator 1 cm in thickness was used. The dimensions were 90 x 90 cm inside length and 90 cm in height. After completion of radiotherapy, the nodular lesions of the skin nearly disappeared. Although the patient survived only 3.5 months after beginning of radiotherapy due to systemic relapse, recurrence of the skin nodule was not seen. In this case TSEBI was therefore a useful treatment for skin infiltration of AMoL.

摘要

一名35岁的急性单核细胞白血病(AMoL)皮肤浸润患者,在诱导化疗后出现广泛的皮肤浸润,接受了全身皮肤电子束照射(TSEBI)治疗。通过活检证实一个皮肤结节为白血病细胞。患者每周接受4次照射,每次剂量为200 cGy,总剂量为1200 cGy,使用来自8个方向的6 MeV电子。治疗分别在身体的上半部分和下半部分进行。焦点-皮肤距离为310 cm。使用厚度为1 cm的丙烯酸板施源器。其内部尺寸为90×90 cm,高度为90 cm。放疗结束后,皮肤结节性病变几乎消失。尽管患者在放疗开始后仅存活了3.5个月就因全身复发而死亡,但未见皮肤结节复发。因此,在这种情况下,TSEBI是治疗AMoL皮肤浸润的一种有效方法。

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