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伴有硬脑膜静脉窦侵犯及颈静脉延伸的脑膜瘤。

Meningioma with dural venous sinus invasion and jugular vein extension.

作者信息

Vachhrajani Shobhan, Jea Andrew, Rutka John A, Blaser Susan, Cusimano Michael, Rutka James T

机构信息

Divisions of Neurosurgery and, The Hospital for Sick Children, University of Toronto, Ontario, Canada.

出版信息

J Neurosurg Pediatr. 2008 Dec;2(6):391-6. doi: 10.3171/PED.2008.2.12.391.

Abstract

Meningiomas represent the most common benign intracranial neoplasm in adults, with a considerably lower incidence in children. The authors present the case of an intracranial meningioma with invasion of, and intraluminal extension into, the transverse and sigmoid sinuses, jugular bulb, and internal jugular vein, resulting in venous occlusion in a 14-year-old girl. Computed tomography scanning, MR imaging, and conventional angiography were performed preoperatively. The patient underwent a 2-stage resection: the supratentorial component was resected first, and the infratentorial and venous sinus and jugular vein components were subsequently removed using a combined skull base approach. Gross-total resection was achieved by opening the lateral dural sinus and removing the meningioma from within the transverse and sigmoid sinuses, the jugular bulb, and the internal jugular vein. The patient remained neurologically intact after the staged tumor resections. Postoperative imaging confirmed the gross-total resection. This case illustrates the unusual property of an intracranial meningioma to invade the intrasinusoidal space and extend into the jugular vein without adherence to the underlying venous endothelium of the jugular vein.

摘要

脑膜瘤是成人最常见的颅内良性肿瘤,在儿童中的发病率则低得多。作者报告了一例14岁女孩的颅内脑膜瘤病例,该肿瘤侵犯并向横窦、乙状窦、颈静脉球和颈内静脉腔内延伸,导致静脉闭塞。术前进行了计算机断层扫描、磁共振成像和传统血管造影。患者接受了两阶段切除术:先切除幕上部分,随后采用联合颅底入路切除幕下、静脉窦和颈静脉部分。通过打开外侧硬脑膜窦并从横窦、乙状窦、颈静脉球和颈内静脉内切除脑膜瘤,实现了肿瘤全切。分期肿瘤切除术后患者神经功能保持完好。术后影像学检查证实了肿瘤全切。该病例说明了颅内脑膜瘤的一种特殊性质,即侵犯静脉窦内空间并延伸至颈静脉,而不附着于颈静脉的下层静脉内皮。

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