Benzel E C, Mirfakhraee M, Hadden T A
Division of Neurosurgery, University of New Mexico School of Medicine, Albuquerque, NM 87131.
AJNR Am J Neuroradiol. 1991 Jan-Feb;12(1):143-7.
Functional positive-contrast shuntography includes a patency check of both limbs of the shunt and the shunt valve by fluoroscopy following the injection of an iodinated contrast agent (anatomic shuntogram) and an assessment of the adequacy of ventricular fluid drainage under physiologic conditions by using serial CT scans to assess the rate of iodine dissipation from the ventricular system (physiologic shuntogram). To demonstrate its efficacy and utility, 82 functional shuntograms were obtained in 55 patients. Fifty-one of the 82 studies were abnormal. Of these, 22 demonstrated patency of both the proximal and distal limbs with an accompanying slow dissipation of contrast material after injection (21 of 22 patients were adults). Eighteen of these 22 patients improved following the reduction of shunt drainage pressure. In the case of frank shunt obstruction, the site of obstruction was delineated clearly in all 29 cases. Correlation of clinical outcome with test results confirmed the utility of this technique, especially when applied to the shunted adult hydrocephalic patient whose response to the shunt had been inadequate. The technique described here allows the clinician to differentiate between physiologic and anatomic shunt failure and between shunt failure and normal shunt function. It also allows for precise localization of the shunt obstruction in anatomic shunt failure and for demonstration of physiologic shunt failure when shunt patency is demonstrated in the presence of the slow dissipation of intraventricular contrast medium.
功能性阳性对比分流造影包括在注入碘化造影剂后通过荧光透视检查分流管的两个分支和分流阀的通畅情况(解剖分流造影),以及通过使用系列CT扫描评估碘从脑室系统消散的速率来评估生理条件下脑室液引流的充分性(生理分流造影)。为了证明其有效性和实用性,对55例患者进行了82次功能性分流造影。82项研究中有51项异常。其中,22项显示近端和远端分支均通畅,注射后造影剂消散缓慢(22例患者中有21例为成年人)。这22例患者中有18例在降低分流引流压力后病情改善。在明显的分流梗阻病例中,所有29例均能清晰显示梗阻部位。临床结果与检查结果的相关性证实了该技术的实用性,尤其是应用于对分流反应不足的成年脑积水患者时。本文所述技术使临床医生能够区分生理性和解剖性分流失败,以及分流失败与正常分流功能。它还能在解剖性分流失败时精确确定分流梗阻的位置,并在脑室造影剂消散缓慢且分流通畅的情况下显示生理性分流失败。