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Muscarinic acetylcholine receptors: structure and function.

作者信息

Hulme E C, Kurtenbach E, Curtis C A

机构信息

Division of Physical Biochemistry, National Institute for Medical Research, Mill Hill, London, U.K.

出版信息

Biochem Soc Trans. 1991 Feb;19(1):133-8. doi: 10.1042/bst0190133.

DOI:10.1042/bst0190133
PMID:1903735
Abstract
摘要

相似文献

1
Muscarinic acetylcholine receptors: structure and function.毒蕈碱型乙酰胆碱受体：结构与功能
Biochem Soc Trans. 1991 Feb;19(1):133-8. doi: 10.1042/bst0190133.
2
Agonist activation of muscarinic acetylcholine receptors.
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3
Structure and function of muscarinic receptors.
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Molecular genetics of signal transduction by muscarinic acetylcholine receptors.毒蕈碱型乙酰胆碱受体信号转导的分子遗传学
Soc Gen Physiol Ser. 1990;45:105-15.
5
Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions.毒蕈碱型乙酰胆碱受体的突变分析：配体/受体/G蛋白相互作用的结构基础
Life Sci. 1993;53(19):1447-63. doi: 10.1016/0024-3205(93)90618-d.
6
Immunological and molecular biological analysis of the regulation and function of muscarinic acetylcholine receptors and G proteins.毒蕈碱型乙酰胆碱受体和G蛋白的调节与功能的免疫学和分子生物学分析
Soc Gen Physiol Ser. 1990;45:133-41.
7
Molecular basis of muscarinic acetylcholine receptor function.毒蕈碱型乙酰胆碱受体功能的分子基础。
Trends Pharmacol Sci. 1993 Aug;14(8):308-13. doi: 10.1016/0165-6147(93)90049-p.
8
Constitutive activity of muscarinic acetylcholine receptors.
J Recept Signal Transduct Res. 2006;26(1-2):61-85. doi: 10.1080/10799890600567349.
9
The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors.G蛋白偶联受体激酶在毒蕈碱型胆碱能受体调节中的作用。
Prog Brain Res. 1996;109:169-79. doi: 10.1016/s0079-6123(08)62099-3.
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Muscarinic acetylcholine receptors: structural basis of ligand binding and G protein coupling.毒蕈碱型乙酰胆碱受体：配体结合和G蛋白偶联的结构基础。
Life Sci. 1995;56(11-12):915-22. doi: 10.1016/0024-3205(95)00028-5.

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Polysorbate-80 surface modified nano-stearylamine BQCA conjugate for the management of Alzheimer's disease.聚山梨醇酯-80表面修饰的纳米硬脂胺BQCA偶联物用于阿尔茨海默病的治疗
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Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors.
膜胆固醇的变化对M1和M3毒蕈碱型乙酰胆碱受体的优先和非优先信号传导产生不同影响。
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Designing human m1 muscarinic receptor-targeted hydrophobic eigenmode matched peptides as functional modulators.设计靶向人M1毒蕈碱受体的疏水本征模匹配肽作为功能调节剂。
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Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors.
Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):3103-7. doi: 10.1073/pnas.90.7.3103.
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Two amino acids, located in transmembrane domains VI and VII, determine the selectivity of the peptide agonist SMS 201-995 for the SSTR2 somatostatin receptor.位于跨膜结构域VI和VII中的两种氨基酸决定了肽激动剂SMS 201-995对生长抑素受体2（SSTR2）的选择性。
EMBO J. 1995 Feb 15;14(4):727-35. doi: 10.1002/j.1460-2075.1995.tb07051.x.
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Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor.
EMBO J. 1993 Jan;12(1):331-8. doi: 10.1002/j.1460-2075.1993.tb05661.x.
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Site-directed mutagenesis of the m3 muscarinic receptor: identification of a series of threonine and tyrosine residues involved in agonist but not antagonist binding.M3毒蕈碱受体的定点诱变：鉴定一系列参与激动剂而非拮抗剂结合的苏氨酸和酪氨酸残基。
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