Lee S Y, Goh B K, Tan Y M, Chung Y F, Cheow P C, Chow P K, Wong W K, Ooi L L
Department of General Surgery, Singapore General Hospital, Outram Road, Singapore.
Singapore Med J. 2008 Nov;49(11):883-5.
Splenectomy is routinely performed in conventional distal pancreatectomies. Spleen removal with its possible sequelae of infections and haematological complications has prompted the development of spleen-preserving techniques. This study aimed to evaluate the safety and clinical outcomes of distal pancreatectomy with preservation of the spleen.
A retrospective review of 24 consecutive patients who underwent spleen-preserving distal pancreatectomy in a tertiary care hospital was conducted.
There were 17 female and seven male patients, and the mean age was 47 (range 14-77) years. Median American Society of Anesthesiologists score was II (range I-III) . The indications were as follows : mucinous cystadenoma (n = 7), serous cystadenoma (n = 6), insulinoma (n = 3), intraductal papillary mucinous tumour (n = 2), pseudocyst (n = 3), papillary cystic adenoma (n = 1), neuroendocrine neoplasm (n = 1), and metastatic carcinoma of the thyroid (n = 1). Two patients developed postoperative pancreatic fistula and another two patients developed postoperative ileus with spontaneous resolution. Mean operative time was 172 (range 105-250) minutes. Mean length of postoperative hospital stay was 6.7 (range 5-11) days. There was no perioperative mortality in this series.
Spleen-preserving distal pancreatectomy can be safely performed with low morbidity, and should be considered in the surgical management of distal pancreatic disease.
在传统的远端胰腺切除术中,脾切除术是常规操作。脾脏切除及其可能引发的感染和血液系统并发症促使了保脾技术的发展。本研究旨在评估保留脾脏的远端胰腺切除术的安全性和临床效果。
对一家三级医疗机构中连续24例行保留脾脏的远端胰腺切除术的患者进行回顾性研究。
患者中女性17例,男性7例,平均年龄47岁(范围14 - 77岁)。美国麻醉医师协会评分中位数为II级(范围I - III级)。手术指征如下:黏液性囊腺瘤(n = 7)、浆液性囊腺瘤(n = 6)、胰岛素瘤(n = 3)、导管内乳头状黏液性肿瘤(n = 2)、假性囊肿(n = 3)、乳头状囊性腺瘤(n = 1)、神经内分泌肿瘤(n = 1)、甲状腺转移性癌(n = 1)。2例患者发生术后胰瘘,另外2例患者发生术后肠梗阻,但均自行缓解。平均手术时间为172分钟(范围105 - 250分钟)。术后平均住院时间为6.7天(范围5 - 11天)。本系列中无围手术期死亡病例。
保留脾脏的远端胰腺切除术可以安全实施,并发症发生率低,在远端胰腺疾病的外科治疗中应予以考虑。