Osborne Carl A, Lulich Jody P, Forrester Dru, Albasan Hasan
Veterinary Clinical Sciences Department, Minnesota Urolith Center, College of Veterinary Medicine, University of Minnesota, 1352 Boyd Avenue, St. Paul, MN 55108, USA.
Vet Clin North Am Small Anim Pract. 2009 Jan;39(1):127-41. doi: 10.1016/j.cvsm.2008.10.001.
Results of experimental and clinical investigation have confirmed the importance of dietary modifications in medical protocols designed to promote dissolution and prevention of uroliths. The objectives of medical management of uroliths are to arrest further growth and to promote urolith dissolution by correcting or controlling underlying abnormalities. For therapy to be most effective, it must promote undersaturation of urine with lithogenic crystalloids by 1) increasing the urine solubility of crystalloids, 2) increasing the volume of urine in which crystalloids are dissolved or suspended, and 3) reducing the quantities of lithogenic crystalloids in urine. This article summarizes and applies evidence about nutritional management of urolithiasis derived from experimental and clinical studies of cats and dogs performed at the Minnesota Urolith Center.
实验和临床研究结果证实，在旨在促进尿石溶解和预防尿石形成的医疗方案中，饮食调整具有重要意义。尿石症医疗管理的目标是通过纠正或控制潜在异常来阻止尿石进一步生长并促进其溶解。为使治疗最有效，必须通过以下方式促进尿液相对于致石晶体呈不饱和状态：1）增加晶体在尿液中的溶解度；2）增加溶解或悬浮晶体的尿量；3）减少尿液中致石晶体的量。本文总结并应用了明尼苏达尿石中心对猫和狗进行的实验及临床研究中得出的有关尿石症营养管理的证据。
