来自L1210淋巴瘤耐药亚系的二氢叶酸还原酶。通过亲和层析法进行纯化以及紫外差示分光光度法和圆二色性研究。 - Suppr

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Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.

作者信息

Gupta S V, Greenfield N J, Poe M, Makulu D R, Williams M N, Moroson B A, Bertino J R

出版信息

Biochemistry. 1977 Jul 12;16(14):3073-9. doi: 10.1021/bi00633a005.

DOI:10.1021/bi00633a005

PMID:19040

Abstract

摘要

相似文献

Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.

Biochemistry. 1977 Jul 12;16(14):3073-9. doi: 10.1021/bi00633a005.

Substrate and inhibitor complexes of dihydrofolate reductase from amethopterin-resistant L1210 cells.

Arch Biochem Biophys. 1975 Dec;171(2):435-43. doi: 10.1016/0003-9861(75)90052-1.

Improved purification of tetrahydrofolate dehydrogenase from L1210 leukemia by affinity chromatography.

Biochim Biophys Acta. 1972 Apr 7;268(1):30-4. doi: 10.1016/0005-2744(72)90193-3.

Purification of tetrahydrofolate dehydrogenase by affinity chromatography.

Biochim Biophys Acta. 1972 Apr 7;268(1):35-40. doi: 10.1016/0005-2744(72)90194-5.

Immunologic heterogeneity of dihydrofolate reductase from methotrexate sensitive and resistant L1210 leukemia cells.

Proc Soc Exp Biol Med. 1985 Oct;180(1):98-102. doi: 10.3181/00379727-180-42149.

Multiple forms of L1210 dihydrofolate reductase differing in affinity for methotrexate.

Biochem Biophys Res Commun. 1984 Feb 29;119(1):352-8. doi: 10.1016/0006-291x(84)91658-9.

Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification and properties.

J Biol Chem. 1967 Oct 25;242(20):4771-6.

Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli.

Biochemistry. 1972 Dec 5;11(25):4706-11. doi: 10.1021/bi00775a011.

Dihydrofolate reductase activity and loss of resistance in an antifolate-resistant subline of leukemia L1210 after discontinuation of treatment.

Chem Biol Interact. 1970 Oct;2(3):229-34. doi: 10.1016/0009-2797(70)90025-6.

Folate antagonists covalently linked to carbohydrates: synthesis, properties, and use in the purification of dihydrofolate reductases.

Arch Biochem Biophys. 1972 May;150(1):15-22. doi: 10.1016/0003-9861(72)90004-5.

引用本文的文献

Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

J Cell Biol. 1993 Feb;120(4):865-75. doi: 10.1083/jcb.120.4.865.

A strong protein unfolding activity is associated with the binding of precursor chloroplast proteins to chloroplast envelopes.

Plant Mol Biol. 1993 Oct;23(2):309-24. doi: 10.1007/BF00029007.

Latent membrane perturbation activity of a mitochondrial precursor protein is exposed by unfolding.

EMBO J. 1988 Apr;7(4):1153-8. doi: 10.1002/j.1460-2075.1988.tb02925.x.

Circular-dichroism studies of ligand binding to dihydrofolate reductase from Lactobacillus casei MTX/R.

Biochem J. 1979 Feb 1;177(2):425-32. doi: 10.1042/bj1770425.

Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.

Proc Natl Acad Sci U S A. 1978 Jul;75(7):3201-5. doi: 10.1073/pnas.75.7.3201.

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Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.

作者信息

Gupta S V, Greenfield N J, Poe M, Makulu D R, Williams M N, Moroson B A, Bertino J R

出版信息

Biochemistry. 1977 Jul 12;16(14):3073-9. doi: 10.1021/bi00633a005.

DOI:10.1021/bi00633a005

PMID:19040

Abstract

摘要

相似文献

Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.

Biochemistry. 1977 Jul 12;16(14):3073-9. doi: 10.1021/bi00633a005.

Substrate and inhibitor complexes of dihydrofolate reductase from amethopterin-resistant L1210 cells.

Arch Biochem Biophys. 1975 Dec;171(2):435-43. doi: 10.1016/0003-9861(75)90052-1.

Improved purification of tetrahydrofolate dehydrogenase from L1210 leukemia by affinity chromatography.

Biochim Biophys Acta. 1972 Apr 7;268(1):30-4. doi: 10.1016/0005-2744(72)90193-3.

Purification of tetrahydrofolate dehydrogenase by affinity chromatography.

Biochim Biophys Acta. 1972 Apr 7;268(1):35-40. doi: 10.1016/0005-2744(72)90194-5.

Immunologic heterogeneity of dihydrofolate reductase from methotrexate sensitive and resistant L1210 leukemia cells.

Proc Soc Exp Biol Med. 1985 Oct;180(1):98-102. doi: 10.3181/00379727-180-42149.

Multiple forms of L1210 dihydrofolate reductase differing in affinity for methotrexate.

Biochem Biophys Res Commun. 1984 Feb 29;119(1):352-8. doi: 10.1016/0006-291x(84)91658-9.

Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification and properties.

J Biol Chem. 1967 Oct 25;242(20):4771-6.

Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli.

Biochemistry. 1972 Dec 5;11(25):4706-11. doi: 10.1021/bi00775a011.

Dihydrofolate reductase activity and loss of resistance in an antifolate-resistant subline of leukemia L1210 after discontinuation of treatment.

Chem Biol Interact. 1970 Oct;2(3):229-34. doi: 10.1016/0009-2797(70)90025-6.

Folate antagonists covalently linked to carbohydrates: synthesis, properties, and use in the purification of dihydrofolate reductases.

Arch Biochem Biophys. 1972 May;150(1):15-22. doi: 10.1016/0003-9861(72)90004-5.

引用本文的文献

Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

J Cell Biol. 1993 Feb;120(4):865-75. doi: 10.1083/jcb.120.4.865.

A strong protein unfolding activity is associated with the binding of precursor chloroplast proteins to chloroplast envelopes.

Plant Mol Biol. 1993 Oct;23(2):309-24. doi: 10.1007/BF00029007.

Latent membrane perturbation activity of a mitochondrial precursor protein is exposed by unfolding.

EMBO J. 1988 Apr;7(4):1153-8. doi: 10.1002/j.1460-2075.1988.tb02925.x.

Circular-dichroism studies of ligand binding to dihydrofolate reductase from Lactobacillus casei MTX/R.

Biochem J. 1979 Feb 1;177(2):425-32. doi: 10.1042/bj1770425.

Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.

Proc Natl Acad Sci U S A. 1978 Jul;75(7):3201-5. doi: 10.1073/pnas.75.7.3201.