Tai Huai-Ching, Lai Ming-Kuen, Wang So-Meng, Chueh Shih-Chieh, Yu Hong-Jeng
Department of Urology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Transpl Int. 2009 Apr;22(4):403-7. doi: 10.1111/j.1432-2277.2008.00798.x. Epub 2008 Nov 25.
Haematuria is a common complication following kidney transplantation, but few studies describing post-transplant haematuria have been published. Herein, we investigated the incidence and etiologies of persistent hematuria with kidney transplant patients in Taiwan. The medical records of 189 kidney transplant recipients with functioning grafts were retrospectively reviewed. Any episode of haematuria during routine follow-up was recorded and evaluated. The patient characteristics, possible causes of haematuria and consequent managements were reviewed. Among the 189 patients, 44 patients (23.3%) experienced 45 episodes of persistent haematuria during routine monthly follow-up at our transplant clinic. Thirty-two episodes (71%) were microscopic haematuria and 13 (29%) were gross haematuria. The most prevalent etiology explained for the persistent haematuria in our series was urologic malignancy (19 patients, 42.2%), followed by urinary tract infections (24.5%) and unexplained reasons (17.8%). Furthermore, those patients with persistent haematuria caused by urologic malignancy were also associated with significantly longer duration following transplantation and worse graft function. Haematuria is frequently seen in kidney transplant recipients and the most prevalent cause in our series is urologic malignancy. Those patients were also associated with significantly poorer graft function; however, the mechanism is still unclear.
血尿是肾移植术后常见的并发症，但描述移植后血尿的研究鲜有发表。在此，我们调查了台湾肾移植患者持续性血尿的发生率及病因。回顾性分析了189例移植肾功能良好的肾移植受者的病历。记录并评估常规随访期间的任何血尿事件。对患者特征、血尿可能原因及后续处理进行了分析。189例患者中，44例（23.3%）在我们移植门诊每月的常规随访期间出现45次持续性血尿。32次（71%）为镜下血尿，13次（29%）为肉眼血尿。本系列中持续性血尿最常见的病因是泌尿系统恶性肿瘤（19例，42.2%），其次是尿路感染（24.5%）和不明原因（17.8%）。此外，因泌尿系统恶性肿瘤导致持续性血尿的患者移植后时间也显著更长，移植肾功能更差。血尿在肾移植受者中很常见，本系列中最常见的病因是泌尿系统恶性肿瘤。这些患者的移植肾功能也显著更差；然而，其机制仍不清楚。
