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硫芥中毒在肺部和眼部受累之前出现的泌尿和皮肤并发症:一种不寻常的症状顺序。

Urinary and cutaneous complications of sulphur mustard poisoning preceding pulmonary and ocular involvement: an unusual sequence of symptoms.

作者信息

Emadi S N, Moeineddin F, Sorush M R

机构信息

Janbazan Medical and Engineering Research Center, Tehran, Iran.

出版信息

Clin Exp Dermatol. 2009 Jul;34(5):e7-10. doi: 10.1111/j.1365-2230.2008.02965.x. Epub 2009 Nov 27.

Abstract

Sulphur mustard was used as a disabling chemical warfare agent during World War I, and, in more recent times, the Iran-Iraq conflict. Various chronic and acute complications have been documented in almost 100,000 Iranian victims to date. Several individual and environmental factors affect the severity and persistency of the complications. The most common adverse effects occur in the respiratory system, skin and eyes, with ocular and respiratory features usually preceding cutaneous lesions. In this paper, we present the unusual case of a chemical victim presenting with characteristic mustard scar leading to stenosis of the external meatus. In this case, initial cutaneous involvement of the injured external genitalia and thighs preceded the ocular and respiratory symptoms. We discuss the possible aetiologies.

摘要

第一次世界大战期间以及最近的两伊冲突中,硫芥被用作一种致伤性化学战剂。迄今为止,近10万名伊朗受害者身上出现了各种急慢性并发症。多种个体因素和环境因素会影响并发症的严重程度和持续性。最常见的不良反应发生在呼吸系统、皮肤和眼睛,眼部和呼吸道症状通常先于皮肤损伤出现。在本文中,我们报告了一例特殊病例,一名化学战受害者出现了典型的芥子气瘢痕,导致外耳道狭窄。该病例中,受伤的外生殖器和大腿最初出现皮肤损伤,随后才出现眼部和呼吸道症状。我们对可能的病因进行了讨论。

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