Shohrati Majid, Peyman Mohammadreza, Peyman Alireza, Davoudi Masoud, Ghanei Mostafa
Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Cutan Ocul Toxicol. 2007;26(2):73-81. doi: 10.1080/15569520701212399.
Although sulfur mustard (SM) has been used as a chemical warfare agent since the early twentieth century, it has reemerged in the past decade as a major threat around the world. This agent injured over 100,000 Iranians and one-third is suffering from late effects until today. Mustard affects many organs such as the skin, eyes, and lungs, as well as the gastrointestinal, endocrine, and hematopoietic system. In this study we focused on review of the late Cutaneous and ocular complications caused by exposure to SM. All studies regarding long-term ocular and cutaneous effects, which have been done on Iranian population, were collected from domestic and international sources. Pruritus is the most common complain and a malignant change is the most important lesion, which has to be considered. Also this agent is causes of chronic and delayed destructive lesions in the ocular surface and cornea, leading to progressive visual deterioration and ocular irritation.
尽管自20世纪初以来，硫芥（SM）就一直被用作化学战剂，但在过去十年中，它再次成为全球的重大威胁。这种毒剂曾致使超过10万名伊朗人受伤，直至今日仍有三分之一的人遭受着后期影响。芥子气会影响许多器官，如皮肤、眼睛和肺部，以及胃肠道、内分泌和造血系统。在本研究中，我们着重回顾了接触硫芥后导致的皮肤和眼部晚期并发症。所有关于伊朗人群长期眼部和皮肤影响的研究，均从国内外来源收集。瘙痒是最常见的主诉，而恶性病变是必须考虑的最重要病变。此外，这种毒剂还会导致眼表和角膜的慢性和延迟性破坏性病变，从而导致视力逐渐下降和眼部刺激。
