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心脏代谢综合征和肥胖症的外科治疗

Surgical treatment of the cardiometabolic syndrome and obesity.

作者信息

Khan Khurshid Ahmad, Sowers James R

机构信息

Post Graduate Medical Institute, Lahore General Hospital, University of Health Sciences Lahore, Lahore, Pakistan.

出版信息

J Cardiometab Syndr. 2008 Fall;3(4):254-7. doi: 10.1111/j.1559-4572.2008.00021.x.

Abstract

Prevalence of overweight and obesity has reached a pandemic proportion worldwide and is increasingly contributing to premature morbidity and mortality. Lifestyle changes including behavioral modification, exercise, different dietary plans, and medications have very poor outcome on long-term weight loss. Bariatric surgery has shown to be very effective for morbidly obese patients. Surgery in these patients not only decreases their body weight but also may improve comorbid conditions associated with obesity. These patients on average lose 61% of excess body weight depending on the procedure performed. Diabetes, hyperlipidemia, and hypertension are normalized in these patients by 77%, 70%, and 62%, respectively. Patients need to be selected carefully for surgical treatment of obesity and have to be monitored closely over the long term for nutritional deficiencies and other complications.

摘要

超重和肥胖在全球范围内已达到流行程度,并越来越多地导致过早发病和死亡。包括行为改变、运动、不同饮食计划和药物治疗在内的生活方式改变对长期减肥效果甚微。减肥手术已被证明对病态肥胖患者非常有效。这些患者接受手术后不仅体重减轻,还可能改善与肥胖相关的合并症。根据所实施的手术程序,这些患者平均可减轻61%的多余体重。糖尿病、高脂血症和高血压在这些患者中的缓解率分别为77%、70%和62%。对于肥胖症的手术治疗,需要仔细挑选患者,并且必须长期密切监测其营养缺乏和其他并发症情况。

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