Ishimoto Yoshiyuki, Hattori Koji, Ohgushi Hajime
Nara Medical University, Department of Orthopaedic surgery.
Clin Calcium. 2008 Dec;18(12):1775-80.
The self-healing capacity of articular cartilage for repair is limited. For articular cartilage injury, several surgical techniques are used in clinical practice, namely drilling, abrasion arthroplasty, microfracture, or autologous osteochondral grafting, while various methods of autologous chondrocyte transplantation to cartilage defect sites have been reported since 1990s. In a case of chondrocyte transplantation to cartilage defect site, the use of proper scaffold is important. Currently, collagen gel or PLGA is used widely as a scaffold.
关节软骨的自我修复能力有限。对于关节软骨损伤，临床实践中使用了几种手术技术，即钻孔、磨削关节成形术、微骨折或自体骨软骨移植，自20世纪90年代以来，还报道了多种将自体软骨细胞移植到软骨缺损部位的方法。在将软骨细胞移植到软骨缺损部位的情况下，使用合适的支架很重要。目前，胶原凝胶或聚乳酸-羟基乙酸共聚物（PLGA）被广泛用作支架。
