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颈动脉支架置入术后再狭窄的影响因素。

Factors influencing restenosis after carotid artery stenting.

作者信息

Van Laanen J, Hendriks J M, Van Sambeek M R H M

机构信息

Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands.

出版信息

J Cardiovasc Surg (Torino). 2008 Dec;49(6):743-7.

Abstract

Many studies have published perioperative clinical results, but the incidence of restenosis and late stroke after carotid artery stenosis is poorly documented. Duplex ultrasonography is the most commonly used technique to follow in-stent restenosis after carotid aretery stenting (CAS), but, the ultrasound criteria for determining a restenosis after stent implantation are very heterogeneous. This review of the literature showed that the long-term in-stent restenosis rate after CAS appears to be acceptable and that restenosis is mainly asymptomatic. Suggested predictors of in-stent restenosis after CAS are advanced age, female gender, implantation of multiple stents, prior revascularization treatment, suboptimal result with residual stenosis, elevated postprocedural serum levels of acute-phase reactants, asymptomatic lesion, use of balloon expandable stents.

摘要

许多研究都发表了围手术期的临床结果,但颈动脉狭窄后再狭窄和晚期中风的发生率记录不足。双功超声检查是颈动脉支架置入术(CAS)后随访支架内再狭窄最常用的技术,但是,支架植入后确定再狭窄的超声标准非常不一致。这篇文献综述表明,CAS后长期支架内再狭窄率似乎是可以接受的,而且再狭窄主要是无症状的。CAS后支架内再狭窄的预测因素包括高龄、女性、多个支架植入、既往血管重建治疗、残余狭窄的不理想结果、术后急性期反应物血清水平升高、无症状病变、使用球囊扩张支架。

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