Mengistu Demmelash H, May Sylvio
Department of Physics, North Dakota State University, Fargo, North Dakota 58105-5566, USA.
J Chem Phys. 2008 Sep 28;129(12):121105. doi: 10.1063/1.2990746.
The nonlinear Poisson-Boltzmann model is used to derive analytical expressions for the free energies of both mixed anionic-zwitterionic and mixed cationic-zwitterionic lipid membranes as function of the mole fraction of charged lipids. Accounting explicitly for the electrostatic properties of the zwitterionic lipid species affects the free energy of anionic and cationic membranes in a qualitatively different way: That of an anionic membrane changes monotonously as a function of the mole fraction of charged lipids, whereas it passes through a pronounced minimum for a cationic membrane.
非线性泊松-玻尔兹曼模型用于推导混合阴离子-两性离子和混合阳离子-两性离子脂质膜的自由能作为带电脂质摩尔分数的函数的解析表达式。明确考虑两性离子脂质种类的静电性质会以定性不同的方式影响阴离子和阳离子膜的自由能：阴离子膜的自由能随带电脂质的摩尔分数单调变化，而阳离子膜的自由能则在某一摩尔分数处出现明显的最小值。
